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integrin beta 7

Summary

Gene Symbol

Itgb7

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16421

PubChem

16421

Alliance of Genome Resources

MGI:96616

Annotation

Keyword

Calcium
Cell adhesion
Cell membrane
Direct protein sequencing
Disulfide bond
EGF-like domain
Glycoprotein
Integrin
Magnesium
Metal-binding
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P26011	Integrin beta-P M290 IEL antigen

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
cell-matrix adhesion involved in ameboidal cell migration	ISO
cell-matrix adhesion involved in ameboidal cell migration	IEA
cell-matrix adhesion	ISO
cell-matrix adhesion	IBA
integrin-mediated signaling pathway	ISO

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration

mononuclear cell migration [inference]

lymphocyte migration [inference]

T cell migration

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

cell-matrix adhesion

cell-matrix adhesion involved in ameboidal cell migration

substrate adhesion-dependent cell spreading

cell adhesion mediated by integrin

cell-cell adhesion

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

heterotypic cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cell motility [inference]

cell migration [inference]

leukocyte migration

mononuclear cell migration [inference]

lymphocyte migration [inference]

T cell migration

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

receptor clustering

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

receptor clustering

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
focal adhesion	IBA
integrin complex	IBA
cell surface	ISO
cell surface	IBA
cell surface	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alpha4-beta7 complex

protein complex involved in cell adhesion [inference]

integrin complex

integrin alpha4-beta7 complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

integrin alpha4-beta7 complex

cellular anatomical entity [inference]

cell surface

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
integrin binding	IBA
metal ion binding	IEA
cell adhesion molecule binding	ISO
cell adhesion molecule binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding

integrin binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Integrin beta

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cell adhesion mediated by integrin
cell migration
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 5** entries
InterPro
Integrin beta subunit, VWA domain
Integrin beta subunit, tail
Integrin beta subunit
Integrin domain superfamily
von Willebrand factor A-like domain superfamily

Ortholog

Displaying entries **1 - 10** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	3688	FB:FBgn0004657
Drosophila melanogaster	3689	FB:FBgn0004657
Drosophila melanogaster	3690	FB:FBgn0004657
Drosophila melanogaster	3693	FB:FBgn0004657
Drosophila melanogaster	3694	FB:FBgn0004657
Homo sapiens	3695	Xenbase:XB-GENE-1012435	HUMAN12925
Drosophila melanogaster	16412	FB:FBgn0004657
Drosophila melanogaster	16414	FB:FBgn0004657
Drosophila melanogaster	16416	FB:FBgn0004657
Drosophila melanogaster	16419	FB:FBgn0004657