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potassium voltage-gated channel, subfamily Q, member 2

Summary

Gene Symbol

Kcnq2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16536

PubChem

16536

Alliance of Genome Resources

MGI:1309503

Annotation

Keyword

Alternative splicing
Cell membrane
Phosphoprotein
Potassium channel
Proteomics identification
Reference proteome
Transmembrane helix
Ubl conjugation
Voltage-gated channel

Proteins

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UniProt	Protein Name
B7ZBV5
A0A0G2JFQ2
B7ZBV8
B7ZBV9
B7ZBV4
Q9Z351	KQT-like 2 Potassium channel subunit alpha KvLQT2 Voltage-gated potassium channel subunit Kv7.2
B7ZBW1
Q3UY10
B7ZBW2
B7ZBV7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 60 in total

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GO Term	Evidence Code	PMID
action potential	IDA	14762142
action potential	IMP	14762142 24687876
protein phosphorylation	IMP	21466805
protein import into nucleus	IMP	20885443
exocytosis	IMP	21466805

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

establishment or maintenance of cell polarity [inference]

establishment of cell polarity

cell death [inference]

programmed cell death [inference]

apoptotic process [inference]

neuron apoptotic process

vesicle-mediated transport [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

pyramidal neuron differentiation [inference]

hippocampal pyramidal neuron differentiation

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to calcium ion

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to calcium ion

cellular response to salt [inference]

cellular response to calcium ion

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

apoptosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

apoptosome assembly

export from cell [inference]

secretion by cell [inference]

exocytosis

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of mechanical stimulus [inference]

sensory perception of sound

transmission of nerve impulse

cognition

learning or memory [inference]

behavior

learning or memory [inference]

motor behavior

psychomotor behavior

determination of adult lifespan

developmental process [inference]

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

anatomical structure development [inference]

animal organ development [inference]

brain development

substantia propria of cornea development

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

pyramidal neuron differentiation [inference]

hippocampal pyramidal neuron differentiation

cell maturation [inference]

neuron maturation [inference]

neuron remodeling

response to stimulus [inference]

response to external stimulus [inference]

response to mechanical stimulus

response to auditory stimulus

response to abiotic stimulus [inference]

response to temperature stimulus

response to mechanical stimulus

response to auditory stimulus

response to chemical [inference]

response to xenobiotic stimulus

cellular response to xenobiotic stimulus

response to organic substance [inference]

response to organic cyclic compound

response to calcium ion [inference]

cellular response to calcium ion

response to inorganic substance [inference]

response to metal ion [inference]

response to calcium ion [inference]

cellular response to calcium ion

cellular response to metal ion [inference]

cellular response to calcium ion

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to calcium ion

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to calcium ion

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to calcium ion

cellular response to salt [inference]

cellular response to calcium ion

response to oxygen-containing compound [inference]

response to calcium ion [inference]

cellular response to calcium ion

cellular response to oxygen-containing compound [inference]

cellular response to calcium ion

response to salt [inference]

response to calcium ion [inference]

cellular response to calcium ion

cellular response to salt [inference]

cellular response to calcium ion

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to metal ion [inference]

cellular response to calcium ion

cellular response to xenobiotic stimulus

cellular response to oxygen-containing compound [inference]

cellular response to calcium ion

cellular response to salt [inference]

cellular response to calcium ion

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

sodium ion transport [inference]

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

vesicle-mediated transport [inference]

secretion [inference]

secretion by cell [inference]

exocytosis

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

organic substance transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

nitrogen compound transport [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

import into cell [inference]

endocytosis

export from cell [inference]

secretion by cell [inference]

exocytosis

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

biological process involved in intraspecies interaction between organisms [inference]

social behavior

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

regulation of action potential [inference]

regulation of action potential firing threshold

regulation of biological quality [inference]

regulation of membrane potential

action potential

regulation of mitochondrial membrane potential [inference]

mitochondrial depolarization

membrane depolarization [inference]

mitochondrial depolarization

membrane hyperpolarization

regulation of action potential [inference]

regulation of action potential firing threshold

regulation of synaptic plasticity

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
mitochondrion	IEA
plasma membrane	ISO
plasma membrane	IDA	16525039
voltage-gated potassium channel complex	ISS
voltage-gated potassium channel complex	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

cell junction [inference]

synapse

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
voltage-gated monoatomic ion channel activity	IGI	12223552
voltage-gated potassium channel activity	ISS
voltage-gated potassium channel activity	ISO
voltage-gated potassium channel activity	IBA
potassium channel activity	IMP	14762142