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kinesin family member 3A

Summary

Gene Symbol

Kif3a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16568

KEGG Gene ID

PubChem

16568

Alliance of Genome Resources

MGI:107689

Annotation

Keyword

3D-structure
ATP-binding
Cilium
Cilium biogenesis/degradation
Coiled coil
Cytoskeleton
Microtubule
Motor protein
Phosphoprotein
Proteomics identification
Reference proteome
Signal

Proteins

Displaying **all 5** entries
UniProt	Protein Name
Q3TET1
Q3UF02
Q3UI47
B1AQZ2
P28741	Microtubule plus end-directed kinesin motor 3A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 44 in total

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GO Term	Evidence Code	PMID
in utero embryonic development	IGI
kidney development	IMP
heart looping	IMP
cilium movement	IMP
microtubule-based movement	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

microtubule anchoring [inference]

microtubule anchoring at microtubule organizing center [inference]

microtubule anchoring at centrosome

microtubule-based movement

cilium movement

transport along microtubule

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

protein acylation [inference]

protein acetylation [inference]

internal protein amino acid acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

macromolecule modification [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

protein acylation [inference]

protein acetylation [inference]

internal protein amino acid acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptidyl-amino acid modification [inference]

peptidyl-lysine modification [inference]

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

protein acylation [inference]

protein acetylation [inference]

internal protein amino acid acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

peptidyl-lysine acetylation [inference]

internal peptidyl-lysine acetylation [inference]

alpha-tubulin acetylation

cell population proliferation [inference]

neural precursor cell proliferation

cell cycle process [inference]

centriole-centriole cohesion

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

microtubule anchoring [inference]

microtubule anchoring at microtubule organizing center [inference]

microtubule anchoring at centrosome

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

inner ear receptor cell stereocilium organization

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

pattern specification process [inference]

regionalization [inference]

anterior/posterior pattern specification

dorsal/ventral pattern formation

dorsal/ventral neural tube patterning

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

epidermal stem cell homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

tube morphogenesis [inference]

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

embryonic morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

epithelial tube morphogenesis [inference]

embryonic heart tube morphogenesis [inference]

heart looping

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

tissue development [inference]

epidermis development

epithelium development [inference]

neural tube development

tube development [inference]

neural tube development

animal organ development [inference]

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

homeostasis of number of cells [inference]

epidermal stem cell homeostasis

response to stimulus [inference]

response to chemical [inference]

response to oxygen-containing compound [inference]

response to silicon dioxide

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport

protein localization to organelle [inference]

protein localization to cilium [inference]

protein localization to non-motile cilium

protein localization to cell junction

establishment of localization [inference]

transport [inference]

protein transport

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

microtubule-based transport [inference]

transport along microtubule

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

cellular localization [inference]

intracellular transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

dendritic transport [inference]

anterograde dendritic transport

anterograde dendritic transport of neurotransmitter receptor complex

receptor localization to synapse [inference]

anterograde dendritic transport of neurotransmitter receptor complex

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of establishment or maintenance of cell polarity regulating cell shape

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of cell shape [inference]

regulation of establishment or maintenance of cell polarity regulating cell shape [inference]

positive regulation of establishment or maintenance of cell polarity regulating cell shape

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

smoothened signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

positive regulation of smoothened signaling pathway

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

regulation of establishment or maintenance of cell polarity [inference]

regulation of establishment or maintenance of cell polarity regulating cell shape [inference]

positive regulation of establishment or maintenance of cell polarity regulating cell shape

regulation of microtubule-based process [inference]

regulation of microtubule-based movement [inference]

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation

regulation of epithelial cell proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of epithelial cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of smoothened signaling pathway

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of establishment or maintenance of cell polarity regulating cell shape

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of intracellular protein transport [inference]

positive regulation of intracellular protein transport

positive regulation of axo-dendritic protein transport

regulation of axo-dendritic protein transport [inference]

positive regulation of axo-dendritic protein transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of biological quality [inference]

regulation of cell shape [inference]

regulation of establishment or maintenance of cell polarity regulating cell shape [inference]

positive regulation of establishment or maintenance of cell polarity regulating cell shape

Displaying entries **11 - 15** of 33 in total

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GO Term	Evidence Code	PMID
spindle microtubule	ISO
cilium	IDA
cilium	IEA
axoneme	ISO
microtubule cytoskeleton	ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

kinesin II complex

cellular anatomical structure [inference]

cytoplasm

neuron projection cytoplasm [inference]

microtubule organizing center [inference]

centrosome

cell junction [inference]

synapse [inference]

ciliary transition zone [inference]

photoreceptor connecting cilium

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

cilium

membraneless organelle [inference]

intracellular membraneless organelle [inference]

centriole

cytoskeleton

microtubule cytoskeleton

intracellular organelle [inference]

intracellular membraneless organelle [inference]

centriole

cytoskeleton

microtubule cytoskeleton

cell body [inference]

neuronal cell body

postsynapse

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

spindle microtubule

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
microtubule motor activity	IDA
microtubule motor activity	IBA
microtubule motor activity	IEA
protein binding	IPI
ATP binding	IEA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

polypeptide conformation or assembly isomerase activity [inference]

microtubule motor activity

binding [inference]

protein binding

cytoskeletal protein binding

tubulin binding [inference]

microtubule binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

GTPase binding [inference]

small GTPase binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080322	polycystic kidney disease	Alliance of Genome Resources
DOID:1934	dysostosis	Alliance of Genome Resources

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	11127	HGNC:6319

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements