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desmoglein 4
Summary
- Gene Symbol
-
- Dsg4
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Calcium
- Cell adhesion
- Cell junction
- Cell membrane
- Cleavage on pair of basic residues
- Disease variant
- Glycoprotein
- Metal-binding
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q7TMD7 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| hair follicle development |
|
|
| cell adhesion |
|
|
| homophilic cell-cell adhesion |
|
|
| keratinocyte differentiation |
|
|
| BMP signaling pathway |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
|
| membrane |
|
|
| desmosome |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding |
|
|
| calcium ion binding |
|
|
| calcium ion binding |
|
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Desmoglein-1
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| calcium ion binding |
| homophilic cell adhesion via plasma membrane adhesion molecules |
| InterPro |
|---|
| Cadherin conserved site |
| Cadherin-like superfamily |
| Cadherin-like |
| Catenin binding domain superfamily |
| Desmosomal cadherin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110703 | hypotrichosis 6 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 291754 | RGD:735015 | |
| 147409 | HGNC:21307 |
