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laminin, alpha 5

Summary

Gene Symbol

Lama5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16776

KEGG Gene ID

PubChem

16776

Alliance of Genome Resources

MGI:105382

Annotation

Keyword

3D-structure
Basement membrane
Cell adhesion
Coiled coil
Direct protein sequencing
Disulfide bond
Glycoprotein
Laminin EGF-like domain
Reference proteome
Repeat
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3TZ05
Q61001	Laminin-10 subunit alpha Laminin-11 subunit alpha Laminin-15 subunit alpha

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
branching involved in ureteric bud morphogenesis	IMP
morphogenesis of a polarized epithelium	IMP
morphogenesis of a polarized epithelium	IEA
neural crest cell migration	IMP
kidney development	IMP

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cellular developmental process [inference]

cell development

cell motility [inference]

cell migration

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cilium organization [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

organelle assembly [inference]

cilium assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly

plasma membrane bounded cell projection organization

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cilium organization [inference]

cilium assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly

postsynapse organization

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

molting cycle process [inference]

hair cycle process [inference]

hair follicle development

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

animal organ morphogenesis

odontogenesis [inference]

odontogenesis of dentin-containing tooth

skeletal system morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in ureteric bud morphogenesis

branching involved in salivary gland morphogenesis

anatomical structure development [inference]

animal organ development [inference]

muscle structure development [inference]

muscle organ development

cellular developmental process [inference]

cell development

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

regulation of developmental process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of cell motility [inference]

regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of embryonic development

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	TAS
extracellular region	IEA
basement membrane	ISO
basement membrane	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

extracellular protein-containing complex [inference]

laminin trimer [inference]

cellular anatomical structure [inference]

extracellular region

cell junction [inference]

synapse

external encapsulating structure [inference]

extracellular matrix

basement membrane

specialized extracellular matrix [inference]

extracellular matrix of synaptic cleft

synaptic cleft

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
signaling receptor binding	IEA
integrin binding	ISO
integrin binding	IDA
integrin binding	IEA
extracellular matrix structural constituent	RCA

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding

signaling receptor binding

integrin binding

cell adhesion molecule binding [inference]

protein-containing complex binding [inference]

integrin binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

laminin

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
P: Inorganic ion transport and metabolism

Displaying **all 2** entries
Gene Ontology
animal organ morphogenesis
tissue development

Displaying **all 5** entries
InterPro
Concanavalin A-like lectin/glucanase domain superfamily
EGF-like domain
Laminin G domain
Laminin IV
Laminin-type EGF domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2975	cystic kidney disease	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	140433	RGD:621023
Caenorhabditis elegans	177956	WB:WBGene00001328
Drosophila melanogaster	38723	FB:FBgn0002526
Homo sapiens	3911	HGNC:6485

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements