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laminin, gamma 2

Summary

Gene Symbol

Lamc2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

16782

PubChem

16782

Alliance of Genome Resources

MGI:99913

Annotation

Keyword

Basement membrane
Cell adhesion
Coiled coil
Disulfide bond
Heparin-binding
Laminin EGF-like domain
Proteoglycan
Proteomics identification
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
G5E874	Epiligrin subunit gamma Kalinin subunit gamma Kalinin/nicein/epiligrin 100 kDa subunit Laminin B2t chain Laminin-5 subunit gamma Nicein subunit gamma

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cell adhesion
axon guidance	IBA
positive regulation of cell population proliferation	ISO
animal organ morphogenesis	IBA
tissue development	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis

anatomical structure development [inference]

tissue development

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular region	TAS
extracellular region	IEA
basement membrane	IDA	11733994 15895400 18757743 9264260
basement membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

extracellular protein-containing complex [inference]

laminin trimer [inference]

cellular anatomical structure [inference]

extracellular region

cytoplasm [inference]

cell cortex

external encapsulating structure [inference]

extracellular matrix

basement membrane

perinuclear region of cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular matrix structural constituent	RCA	22159717
protein binding	IPI	11733994
heparin binding	IDA	11733994

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Laminin subunit gamma-2

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 4** entries
Gene Ontology
animal organ morphogenesis
cell migration
integrin binding
morphogenesis of a polarized epithelium

Displaying **all 3** entries
InterPro
EGF-like domain
Laminin IV
Laminin-type EGF domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060737	junctional epidermolysis bullosa Herlitz type	Alliance of Genome Resources
DOID:0060738	junctional epidermolysis bullosa non-Herlitz type	Alliance of Genome Resources