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acid-sensing ion channel 3

Summary

Gene Symbol

Asic3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

171209

PubChem

171209

Alliance of Genome Resources

MGI:2159339

Annotation

Keyword

Alternative splicing
Cell membrane
Cytoplasm
Disulfide bond
Glycoprotein
Phosphoprotein
Reference proteome
Sodium channel
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6X1Y6	Amiloride-sensitive cation channel 3 Dorsal root ASIC

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
monoatomic cation transport	IDA	11854527
monoatomic cation transport	IMP	11854527
sodium ion transport	ISO
response to heat	IMP	11754838 12060708
response to mechanical stimulus	IMP	11754838 12060708

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of taste [inference]

sensory perception of sour taste

response to stimulus [inference]

response to stress [inference]

response to heat

response to external stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

response to heat

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

response to pH [inference]

response to acidic pH

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

response to mechanical stimulus

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

detection of stimulus [inference]

detection of external stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

detection of abiotic stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus [inference]

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

detection of chemical stimulus [inference]

detection of chemical stimulus involved in sensory perception

detection of chemical stimulus involved in sensory perception of pain

detection of stimulus involved in sensory perception [inference]

detection of chemical stimulus involved in sensory perception

detection of chemical stimulus involved in sensory perception of pain

detection of temperature stimulus involved in sensory perception

detection of temperature stimulus involved in sensory perception of pain

detection of mechanical stimulus involved in sensory perception

detection of mechanical stimulus involved in sensory perception of pain

detection of stimulus involved in sensory perception of pain [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport [inference]

iron coordination entity transport [inference]

siderophore transport [inference]

enterobactin transport

sodium ion transport

sodium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

enterobactin transport

organic hydroxy compound transport [inference]

enterobactin transport

establishment of localization in cell

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane potential [inference]

membrane depolarization

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	ISO
plasma membrane	IDA	11854527
plasma membrane	IBA
perinuclear region of cytoplasm	ISO
perinuclear region of cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
monoatomic cation channel activity	TAS	11754838
monoatomic cation channel activity	IDA	11854527
monoatomic cation channel activity	IMP	11854527
ligand-gated sodium channel activity	ISO
ligand-gated sodium channel activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

enterobactin transmembrane transporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

sodium channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity

sodium channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

ligand-gated sodium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

ligand-gated sodium channel activity

siderophore-iron transmembrane transporter activity [inference]

enterobactin transmembrane transporter activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic cation channel activity

sodium channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

ligand-gated sodium channel activity

organic hydroxy compound transmembrane transporter activity [inference]

enterobactin transmembrane transporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

sodium channel activity [inference]

ligand-gated sodium channel activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

acid-sensing ion channel, other

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ligand-gated sodium channel activity
monoatomic ion transport
sodium channel activity
sodium ion transmembrane transport

Displaying 1 entry
InterPro
Epithelial sodium channel

Ortholog

Displaying entries **41 - 50** of 73 in total

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Species	Gene ID	Orthologous MAtrix
Cavia porcellus	100731464	CAVPO13748
Cricetulus griseus	100763386	CRIGR08568
Otolemur garnettii	100954823	OTOGA10155
Pan paniscus	100975981	PANPA37557
Papio anubis	101026648	PAPAN29637
Saimiri boliviensis boliviensis	101036863	SAIBB16596
Gorilla gorilla gorilla	101148703	GORGO39038
Octodon degus	101574604	OCTDE06623
Jaculus jaculus	101595395	JACJA21460
Mustela putorius furo	101676254	MUSPF07630