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CD46 antigen, complement regulatory protein

Summary

Gene Symbol

Cd46

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17221

PubChem

17221

Alliance of Genome Resources

MGI:1203290

Annotation

Keyword

Alternative splicing
Cytoplasmic vesicle
Disulfide bond
Fertilization
Glycoprotein
Reference proteome
Repeat
Secreted
Signal
Sushi
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O88174

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
T cell mediated immunity	ISO
T cell mediated immunity	IBA
single fertilization	IEA
regulation of Notch signaling pathway	ISO
positive regulation of gene expression	ISO

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

T cell mediated immunity

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

reproductive process [inference]

fertilization [inference]

single fertilization

response to stimulus [inference]

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of immune effector process [inference]

positive regulation of memory T cell differentiation

positive regulation of immune response [inference]

positive regulation of memory T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

positive regulation of immune effector process [inference]

positive regulation of memory T cell differentiation

regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of lymphocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of B cell mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of immunoglobulin mediated immune response [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation [inference]

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of immunoglobulin mediated immune response [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response [inference]

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation [inference]

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

positive regulation of immune response [inference]

positive regulation of memory T cell differentiation

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

positive regulation of proteolysis

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

extracellular regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of immune effector process [inference]

positive regulation of memory T cell differentiation

positive regulation of immune response [inference]

positive regulation of memory T cell differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of proteolysis

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

positive regulation of memory T cell differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

extracellular regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

positive regulation of memory T cell differentiation

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of immunoglobulin mediated immune response [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response [inference]

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation [inference]

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

positive regulation of immune response [inference]

positive regulation of memory T cell differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

extracellular regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of leukocyte proliferation [inference]

positive regulation of mononuclear cell proliferation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of cytokine production [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

extracellular negative regulation of signal transduction [inference]

sequestering of extracellular ligand from receptor

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

regulation of interleukin-10 production [inference]

positive regulation of interleukin-10 production

regulation of transforming growth factor beta production [inference]

positive regulation of transforming growth factor beta production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

regulation of lymphocyte activation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

positive regulation of T cell proliferation

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cell activation [inference]

positive regulation of leukocyte activation [inference]

positive regulation of lymphocyte activation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of lymphocyte proliferation [inference]

positive regulation of T cell proliferation

positive regulation of T cell activation [inference]

positive regulation of T cell proliferation

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of leukocyte differentiation [inference]

regulation of lymphocyte differentiation [inference]

regulation of T cell differentiation [inference]

regulation of memory T cell differentiation [inference]

positive regulation of memory T cell differentiation

positive regulation of T cell differentiation [inference]

regulation of regulatory T cell differentiation [inference]

positive regulation of regulatory T cell differentiation

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of lymphocyte differentiation [inference]

positive regulation of T cell differentiation [inference]

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
acrosomal vesicle	ISO
inner acrosomal membrane	ISO
inner acrosomal membrane	IEA
extracellular region	IEA
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

inner acrosomal membrane

plasma membrane region [inference]

basolateral plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endopeptidase activity	ISO
cadherin binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity

binding [inference]

protein binding [inference]

cell adhesion molecule binding [inference]

cadherin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

membrane cofactor protein

Functional Category

E: Amino acid transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Sushi/SCR/CCP domain
Sushi/SCR/CCP superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:10871	age related macular degeneration	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 28 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	350	FB:FBgn0030617
Danio rerio	1380	ZFIN:ZDB-GENE-110411-232
Homo sapiens	4179	ZFIN:ZDB-GENE-041111-283	HUMAN54547
Drosophila melanogaster	6402	FB:FBgn0030617
Drosophila melanogaster	11818	FB:FBgn0030617
Drosophila melanogaster	12946	FB:FBgn0030617
Danio rerio	13136	ZFIN:ZDB-GENE-041111-283
Danio rerio	17221	ZFIN:ZDB-GENE-041111-283
Drosophila melanogaster	20343	FB:FBgn0030617
Drosophila melanogaster	29259	FB:FBgn0030617

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements