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ATP-binding cassette, sub-family C member 1

Summary

Gene Symbol

Abcc1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17250

KEGG Gene ID

PubChem

17250

Alliance of Genome Resources

MGI:102676

Annotation

Keyword

ATP-binding
Cell membrane
Glycoprotein
Hydrolase
Lipid transport
Phosphoprotein
Reference proteome
Repeat
Translocase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A5D6P3	ATP-binding cassette sub-family C member 1 Glutathione-S-conjugate-translocating ATPase ABCC1 Leukotriene C(4) transporter
O35379	ATP-binding cassette sub-family C member 1 Glutathione-S-conjugate-translocating ATPase ABCC1 Leukotriene C(4) transporter

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of **112** in total

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GO Term	Evidence Code	PMID
tissue homeostasis	IMP
granuloma formation	IMP
inflammatory response to antigenic stimulus	IMP
endothelium development	IMP
leukotriene metabolic process	IMP

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

granuloma formation

immune response

inflammatory response to antigenic stimulus

antigen processing and presentation [inference]

antigen processing and presentation via MHC class Ib [inference]

antigen processing and presentation of lipid antigen via MHC class Ib

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

lymphocyte activation [inference]

T cell activation [inference]

alpha-beta T cell activation [inference]

NK T cell activation

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

lymphocyte activation [inference]

T cell activation [inference]

alpha-beta T cell activation [inference]

NK T cell activation

metabolic process [inference]

modified amino acid metabolic process [inference]

glutathione metabolic process

sulfur compound metabolic process [inference]

glutathione metabolic process

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

reactive oxygen species biosynthetic process

hydrogen peroxide biosynthetic process

pteridine-containing compound metabolic process [inference]

tetrahydrobiopterin metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

glucocorticoid metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

diol metabolic process [inference]

tetrahydrobiopterin metabolic process

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process

leukotriene biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

amyloid-beta metabolic process

reactive oxygen species metabolic process [inference]

superoxide metabolic process [inference]

superoxide anion generation

hydrogen peroxide metabolic process [inference]

hydrogen peroxide biosynthetic process

reactive oxygen species biosynthetic process

hydrogen peroxide biosynthetic process

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation

astrocyte differentiation

neurogenesis

cell motility [inference]

cell migration [inference]

leukocyte migration [inference]

mononuclear cell migration [inference]

lymphocyte migration

cell chemotaxis

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to amyloid-beta

transmembrane transport

xenobiotic transmembrane transport

oligopeptide transmembrane transport [inference]

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

import across plasma membrane [inference]

long-chain fatty acid import across plasma membrane

export across plasma membrane

xenobiotic detoxification by transmembrane export across the plasma membrane

carboxylic acid transmembrane transport

fatty acid transmembrane transport [inference]

long-chain fatty acid import across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

export from cell

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane

xenobiotic detoxification by transmembrane export across the plasma membrane

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

lymphocyte activation [inference]

T cell activation [inference]

alpha-beta T cell activation [inference]

NK T cell activation

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier [inference]

xenobiotic transport across blood-brain barrier

blood vessel diameter maintenance

vasodilation

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory

behavior [inference]

learning or memory [inference]

memory

exploration behavior

multicellular organism growth

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

amyloid-beta clearance

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

endothelium development

regeneration [inference]

tissue regeneration [inference]

neural tissue regeneration

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation

astrocyte differentiation

neurogenesis

growth [inference]

developmental growth [inference]

multicellular organism growth

tissue regeneration [inference]

neural tissue regeneration

locomotion [inference]

taxis [inference]

chemotaxis [inference]

cell chemotaxis

homeostatic process [inference]

cellular homeostasis [inference]

cell redox homeostasis

intracellular chemical homeostasis

intracellular nitrogen homeostasis

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis

intracellular nitrogen homeostasis

pigmentation [inference]

pigment accumulation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

inflammatory response to antigenic stimulus

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to oxidative stress

cellular response to stress [inference]

cellular response to DNA damage stimulus

response to fluid shear stress

immune response

inflammatory response to antigenic stimulus

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

pigment accumulation

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

defense response to Gram-positive bacterium

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to chemical [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to amyloid-beta

response to peptide [inference]

response to cytokine [inference]

response to type II interferon

cellular response to type II interferon

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

response to nitrogen compound [inference]

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

response to oxygen-containing compound [inference]

cellular response to oxygen-containing compound [inference]

cellular response to amyloid-beta

response to amyloid-beta [inference]

cellular response to amyloid-beta

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to chemical stimulus [inference]

cellular response to nitrogen compound [inference]

cellular response to amyloid-beta

cellular response to oxygen-containing compound [inference]

cellular response to amyloid-beta

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to cell surface

establishment of localization [inference]

transport [inference]

lipid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

long-chain fatty acid import into cell [inference]

long-chain fatty acid import across plasma membrane

fatty acid transmembrane transport [inference]

long-chain fatty acid import across plasma membrane

phospholipid transport [inference]

lipid translocation [inference]

lipid import into cell [inference]

long-chain fatty acid import into cell [inference]

long-chain fatty acid import across plasma membrane

vascular transport [inference]

transport across blood-brain barrier [inference]

xenobiotic transport across blood-brain barrier

organic anion transport [inference]

glutathione transport

glutathione transmembrane transport

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

bilirubin transport

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

long-chain fatty acid import into cell [inference]

long-chain fatty acid import across plasma membrane

fatty acid transmembrane transport [inference]

long-chain fatty acid import across plasma membrane

icosanoid transport [inference]

leukotriene transport

carboxylic acid transmembrane transport

fatty acid transmembrane transport [inference]

long-chain fatty acid import across plasma membrane

organophosphate ester transport [inference]

nucleotide transport [inference]

cyclic nucleotide transport

phospholipid transport [inference]

peptide transport [inference]

oligopeptide transport [inference]

oligopeptide transmembrane transport [inference]

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

tripeptide transport [inference]

glutathione transport

glutathione transmembrane transport

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

bilirubin transport

monocarboxylic acid transport [inference]

fatty acid transport [inference]

long-chain fatty acid transport [inference]

long-chain fatty acid import into cell [inference]

long-chain fatty acid import across plasma membrane

fatty acid transmembrane transport [inference]

long-chain fatty acid import across plasma membrane

icosanoid transport [inference]

leukotriene transport

carboxylic acid transmembrane transport

fatty acid transmembrane transport [inference]

long-chain fatty acid import across plasma membrane

xenobiotic transport

xenobiotic transmembrane transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

xenobiotic transport across blood-brain barrier

vitamin transport [inference]

cobalamin transport

transmembrane transport

xenobiotic transmembrane transport

oligopeptide transmembrane transport [inference]

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

import across plasma membrane [inference]

long-chain fatty acid import across plasma membrane

export across plasma membrane

xenobiotic detoxification by transmembrane export across the plasma membrane

carboxylic acid transmembrane transport

fatty acid transmembrane transport [inference]

long-chain fatty acid import across plasma membrane

transepithelial transport

nitrogen compound transport [inference]

oligopeptide transport [inference]

oligopeptide transmembrane transport [inference]

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

tripeptide transport [inference]

glutathione transport

glutathione transmembrane transport

tripeptide transmembrane transport [inference]

glutathione transmembrane transport

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

cyclic nucleotide transport

modified amino acid transport [inference]

glutathione transport

glutathione transmembrane transport

sphingolipid translocation

sulfur compound transport [inference]

glutathione transport

glutathione transmembrane transport

import into cell [inference]

long-chain fatty acid import into cell [inference]

long-chain fatty acid import across plasma membrane

import across plasma membrane [inference]

long-chain fatty acid import across plasma membrane

export from cell

xenobiotic export from cell [inference]

xenobiotic detoxification by transmembrane export across the plasma membrane

export across plasma membrane

xenobiotic detoxification by transmembrane export across the plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

regulation of inflammatory response [inference]

positive regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

positive regulation of response to external stimulus [inference]

positive regulation of inflammatory response

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of inflammatory response

regulation of inflammatory response [inference]

positive regulation of inflammatory response

regulation of response to drug [inference]

regulation of cellular response to drug

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cellular response to drug

regulation of biological quality [inference]

regulation of membrane potential

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance

vasodilation

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

regulation of molecular function [inference]

regulation of catalytic activity

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IDA
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

Displaying entries **1 - 5** of 37 in total

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GO Term	Evidence Code	PMID
long-chain fatty acid transmembrane transporter activity	ISO
long-chain fatty acid transmembrane transporter activity	IEA
ATP binding	IEA
ABC-type xenobiotic transporter activity	ISS
ABC-type xenobiotic transporter activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity

efflux transmembrane transporter activity

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled lipid transmembrane transporter activity

ABC-type transporter activity

oligopeptide transmembrane transporter activity [inference]

tripeptide transmembrane transporter activity [inference]

glutathione transmembrane transporter activity

xenobiotic transmembrane transporter activity

ABC-type xenobiotic transporter activity

carboxylic acid transmembrane transporter activity

monocarboxylic acid transmembrane transporter activity [inference]

fatty acid transmembrane transporter activity [inference]

long-chain fatty acid transmembrane transporter activity

modified amino acid transmembrane transporter activity [inference]

glutathione transmembrane transporter activity

vitamin transmembrane transporter activity [inference]

ABC-type vitamin B12 transporter activity

lipid transmembrane transporter activity [inference]

fatty acid transmembrane transporter activity [inference]

long-chain fatty acid transmembrane transporter activity

ATPase-coupled lipid transmembrane transporter activity

sulfur compound transmembrane transporter activity [inference]

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ATPase-coupled lipid transmembrane transporter activity

ABC-type transporter activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:33147

H₂O + ATP + daunorubicin

H⁺ + phosphate + ADP + daunorubicin

Enzyme

7.6.2.2

PMID

9281595

RHEA:19121

H₂O + ATP + an S-substituted glutathione

H⁺ + phosphate + ADP + an S-substituted glutathione

Enzyme

7.6.2.3

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP005578
Gene Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 1

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	24565	RGD:3112
Caenorhabditis elegans	180409	WB:WBGene00003407
Caenorhabditis elegans	180408	WB:WBGene00003408
Homo sapiens	4363	HGNC:51
Saccharomyces cerevisiae S288C	850645	SGD:S000003938

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Guidelines

Summary

External Links

Annotation

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements