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Nicastrin

Summary

Gene Symbol

aph-2

Organism

Caenorhabditis elegans

External Links

NCBI Gene

172905

KEGG Gene ID

PubChem

172905

Alliance of Genome Resources

WB:WBGene00000148

Annotation

Keyword

Glycoprotein
Notch signaling pathway
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q23316	Anterior-pharynx-defective protein 2
A5Z2T7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

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Last »
GO Term	Evidence Code	PMID
Notch signaling pathway	IMP
Notch receptor processing	IBA
protein processing	IBA
protein processing	IEA
egg-laying behavior	IMP

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

Notch receptor processing

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

Notch receptor processing

protein maturation [inference]

protein processing

cellular developmental process [inference]

cell fate commitment [inference]

cell fate commitment involved in pattern specification

reproductive process [inference]

multicellular organismal reproductive process [inference]

reproductive behavior [inference]

egg-laying behavior

multicellular organismal process [inference]

behavior [inference]

reproductive behavior [inference]

egg-laying behavior

developmental process [inference]

anatomical structure morphogenesis [inference]

embryonic morphogenesis

anatomical structure development [inference]

pharynx development [inference]

nematode pharynx development

cellular developmental process [inference]

cell fate commitment [inference]

cell fate commitment involved in pattern specification

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA
plasma membrane	IBA
membrane	IEA
gamma-secretase complex	ISS

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

gamma-secretase complex

catalytic complex [inference]

gamma-secretase complex

cellular anatomical structure [inference]

membrane

plasma membrane

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
plasma membrane	PMID:10804188

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	59287	MGI:1891700
Rattus norvegicus	289231	RGD:631418
Drosophila melanogaster	42964	FB:FBgn0039234
Homo sapiens	23385	HGNC:17091

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

International Collaboration

Acknowledgements