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Ephrin-4

Summary

Gene Symbol

efn-4

Organism

Caenorhabditis elegans

External Links

NCBI Gene

176882

KEGG Gene ID

PubChem

176882

Alliance of Genome Resources

WB:WBGene00001165

Annotation

Keyword

Cell membrane
Developmental protein
Disulfide bond
GPI-anchor
Neurogenesis
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
O44516	Protein male abnormal 26

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
axon guidance	IBA
embryo development ending in birth or egg hatching	IMP
embryo development ending in birth or egg hatching	IGI
morphogenesis of embryonic epithelium	IMP
morphogenesis of embryonic epithelium	IGI

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

ephrin receptor signaling pathway

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

cell migration involved in gastrulation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

multicellular organismal process [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching

developmental process [inference]

anatomical structure morphogenesis [inference]

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of embryonic epithelium

male anatomical structure morphogenesis [inference]

nematode male tail tip morphogenesis

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of chemotaxis [inference]

regulation of axon guidance

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of chemotaxis [inference]

regulation of axon guidance

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

ephrin receptor signaling pathway

regulation of cell adhesion

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of axon guidance

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA
axon	IDA
neuronal cell body	IDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

cell body [inference]

neuronal cell body

side of membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI
ephrin receptor binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

ephrin receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Ephrin

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
ephrin receptor binding
ephrin receptor signaling pathway

Displaying **all 4** entries
InterPro
Cupredoxin
Ephrin receptor-binding domain
Ephrin, conserved site
Ephrin

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
axon	PMID:12403719
neuronal cell body	PMID:12403719

Ortholog

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Species	Gene ID	Alliance of Genome Resources
Mus musculus	13636	MGI:103236
Mus musculus	13638	MGI:106644
Mus musculus	13640	MGI:107444
Mus musculus	13639	MGI:106643
Mus musculus	13637	MGI:102707
Rattus norvegicus	94268	RGD:620388
Rattus norvegicus	116683	RGD:620391
Homo sapiens	1944	HGNC:3223
Homo sapiens	1942	HGNC:3221
Homo sapiens	1946	HGNC:3225

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements