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MIRAGE
A disintegrin and metalloproteinase with thrombospondin motifs gon-1;Peptidase M12B domain-containing protein

Summary
Gene Symbol
  • gon-1
Organism
Caenorhabditis elegans
NCBI Gene
177850
PubChem
177850
Alliance of Genome Resources
Annotation
Keyword
  • Basement membrane
  • Calcium
  • Developmental protein
  • Disulfide bond
  • ER-Golgi transport
  • Endoplasmic reticulum
  • Glycoprotein
  • Golgi apparatus
  • Metal-binding
  • Metalloprotease
  • Protein transport
  • Proteomics identification
  • Reference proteome
  • Repeat
  • Signal
  • Zinc
  • Zymogen
Proteins
Displaying all 2 entries
UniProt Protein Name
H2L2A7
Q19791
  • Abnormal gonad development protein 1
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 12 in total
GO Term Evidence Code PMID
proteolysis
proteolysis
endoplasmic reticulum to Golgi vesicle-mediated transport
gonad development
anatomical structure morphogenesis
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
thrombospondin
Functional Category
  • G: Carbohydrate transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 7 entries
Gene Ontology
extracellular matrix organization
hydrolase activity
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis
zinc ion binding
Displaying all 10 entries
InterPro
ADAMTS, cysteine-rich domain 2
ADAMTS/ADAMTS-like, Spacer 1
ADAMTS/ADAMTS-like, cysteine-rich domain 3
ADAMTS/ADAMTS-like
Metallopeptidase, catalytic domain superfamily
Peptidase M12B, ADAM/reprolysin
Peptidase M12B, GON-ADAMTSs
Peptidase M12B, propeptide
Thrombospondin type-1 (TSP1) repeat superfamily
Thrombospondin type-1 (TSP1) repeat
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:9352 type 2 diabetes mellitus
DOID:9970 obesity
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026