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dynein cytoplasmic 1 light intermediate chain 2

Summary

Gene Symbol

DYNC1LI2

Organism

Homo sapiens (human)

External Links

NCBI Gene

1783

KEGG Gene ID

PubChem

1783

Alliance of Genome Resources

HGNC:2966

Annotation

Keyword

3D-structure
ATP-binding
Alternative splicing
Cytoskeleton
Dynein
Methylation
Microtubule
Motor protein
Phosphoprotein
Proteomics identification
Reference proteome
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
O43237	Dynein light intermediate chain 2, cytosolic LIC53/55

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	IBA
microtubule-based movement	IBA
microtubule-based movement	IEA
positive regulation of intracellular transport	NAS
centrosome localization

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule organizing center localization [inference]

centrosome localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

response to nerve growth factor [inference]

cellular response to nerve growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to nerve growth factor stimulus

localization [inference]

microtubule organizing center localization [inference]

centrosome localization

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport

positive regulation of transport [inference]

positive regulation of intracellular transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport

positive regulation of transport [inference]

positive regulation of intracellular transport

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport

Displaying entries **1 - 5** of 13 in total

1

2

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GO Term	Evidence Code	PMID
kinetochore	IEA
male germ cell nucleus	NAS
late endosome	IEA
centrosome	IDA
centrosome	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex [inference]

cytoplasmic dynein complex

catalytic complex [inference]

dynein complex [inference]

cytoplasmic dynein complex

cellular anatomical structure [inference]

microtubule organizing center [inference]

centrosome

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membrane-bounded organelle [inference]

nucleus [inference]

germ cell nucleus [inference]

male germ cell nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

membraneless organelle [inference]

intracellular membraneless organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus [inference]

germ cell nucleus [inference]

male germ cell nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membraneless organelle [inference]

supramolecular complex [inference]

kinetochore

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ATP binding
identical protein binding	IEA
dynein heavy chain binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

cytoplasmic dynein 1 light intermediate chain 1

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
dynein heavy chain binding
microtubule cytoskeleton organization
microtubule-based movement
nucleotide binding

Displaying **all 3** entries
InterPro
Dynein 1 light intermediate chain
Dynein family light intermediate chain
P-loop containing nucleoside triphosphate hydrolase

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Last updated: April 6, 2026

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