GlyCosmos Portal

Submissions

myosin, heavy polypeptide 6, cardiac muscle, alpha

Summary

Gene Symbol

Myh6

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

17888

KEGG Gene ID

PubChem

17888

Alliance of Genome Resources

MGI:97255

Annotation

Keyword

3D-structure
ATP-binding
Actin-binding
Calmodulin-binding
Coiled coil
Cytoplasm
Methylation
Myosin
Phosphoprotein
Reference proteome
Thick filament

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q02566	Myosin heavy chain 6 Myosin heavy chain, cardiac muscle alpha isoform
B2RQQ1	Myosin heavy chain 6 Myosin heavy chain, cardiac muscle alpha isoform

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 35 in total

1

2

3

4

5

…

Next ›

Last »
GO Term	Evidence Code	PMID
in utero embryonic development	IMP
regulation of the force of heart contraction	ISO
regulation of the force of heart contraction	IMP
regulation of the force of heart contraction	IEA
regulation of heart rate	ISO

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

nucleoside triphosphate metabolic process [inference]

purine nucleoside triphosphate metabolic process [inference]

purine ribonucleoside triphosphate metabolic process [inference]

ATP metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

ATP metabolic process

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

actin filament-based movement

actin-mediated cell contraction [inference]

actin-myosin filament sliding [inference]

muscle filament sliding

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

striated muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

organelle assembly [inference]

membraneless organelle assembly [inference]

myofibril assembly

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly

organelle assembly [inference]

membraneless organelle assembly [inference]

myofibril assembly

supramolecular fiber organization [inference]

myofibril assembly

multicellular organismal process [inference]

system process [inference]

muscle system process [inference]

muscle contraction

striated muscle contraction

cardiac muscle contraction

muscle hypertrophy [inference]

muscle hypertrophy in response to stress [inference]

cardiac muscle hypertrophy in response to stress

striated muscle hypertrophy [inference]

cardiac muscle hypertrophy [inference]

cardiac muscle hypertrophy in response to stress

muscle adaptation [inference]

muscle hypertrophy in response to stress [inference]

cardiac muscle hypertrophy in response to stress

striated muscle adaptation [inference]

cardiac muscle adaptation [inference]

cardiac muscle hypertrophy in response to stress

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

developmental process [inference]

anatomical structure morphogenesis [inference]

tissue morphogenesis [inference]

muscle tissue morphogenesis [inference]

cardiac muscle tissue morphogenesis [inference]

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

myofibril assembly

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

cell development [inference]

muscle cell development [inference]

striated muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

animal organ development [inference]

heart development [inference]

adult heart development

muscle organ development [inference]

visceral muscle development

muscle structure development [inference]

muscle organ development [inference]

visceral muscle development

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

striated muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

response to stimulus [inference]

response to stress [inference]

muscle hypertrophy in response to stress [inference]

cardiac muscle hypertrophy in response to stress

muscle adaptation [inference]

muscle hypertrophy in response to stress [inference]

cardiac muscle hypertrophy in response to stress

striated muscle adaptation [inference]

cardiac muscle adaptation [inference]

cardiac muscle hypertrophy in response to stress

biological regulation [inference]

regulation of biological process [inference]

regulation of growth [inference]

regulation of developmental growth [inference]

regulation of organ growth [inference]

regulation of heart growth

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of organ growth [inference]

regulation of heart growth

regulation of multicellular organismal development [inference]

regulation of heart growth

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of heart contraction

regulation of organ growth [inference]

regulation of heart growth

regulation of multicellular organismal development [inference]

regulation of heart growth

regulation of biological quality [inference]

regulation of molecular function [inference]

regulation of ATP-dependent activity

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
stress fiber	IDA
stress fiber	IEA
cytoplasm	IBA
muscle myosin complex	ISO
myosin complex	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

myosin complex

myosin II complex

muscle myosin complex

cellular anatomical structure [inference]

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

contractile muscle fiber [inference]

myofibril

intracellular organelle [inference]

intracellular membraneless organelle [inference]

contractile muscle fiber [inference]

myofibril

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

myosin filament

contractile muscle fiber [inference]

myofibril

Displaying entries **1 - 5** of 16 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
microfilament motor activity	ISO
microfilament motor activity	IMP
microfilament motor activity	IBA
microfilament motor activity	IEA
cytoskeletal motor activity	IEA

GO Hierarchy

molecular function

cytoskeletal motor activity

microfilament motor activity

catalytic activity [inference]

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

polypeptide conformation or assembly isomerase activity [inference]

microfilament motor activity

binding [inference]

protein binding

calmodulin binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding

actin filament binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

ATP-dependent activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0110453	dilated cardiomyopathy 1EE	Alliance of Genome Resources
DOID:12930	dilated cardiomyopathy	Alliance of Genome Resources
DOID:0110320	hypertrophic cardiomyopathy 14	Alliance of Genome Resources