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MIRAGE
dopamine receptor D2
Summary
- Gene Symbol
-
- DRD2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Golgi apparatus
- Palmitate
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| temperature homeostasis |
|
|
| response to hypoxia |
|
|
| synaptic transmission, dopaminergic |
|
|
| response to amphetamine |
|
|
| response to amphetamine |
|
GO Hierarchy
- pigmentation
biological process
cellular process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
regulation of trans-synaptic signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
regulation of trans-synaptic signaling [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of secretion by cell
regulation of multicellular organismal process [inference]
regulation of biological quality [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane |
|
|
| Golgi membrane |
|
|
| acrosomal vesicle |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| dopamine neurotransmitter receptor activity, coupled via Gi/Go |
|
|
| dopamine neurotransmitter receptor activity, coupled via Gi/Go |
|
|
| dopamine neurotransmitter receptor activity, coupled via Gi/Go |
|
|
| G-protein alpha-subunit binding |
|
|
| G protein-coupled receptor activity |
|
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9976 | heroin dependence | |
| DOID:2030 | anxiety disorder | |
| DOID:9975 | cocaine dependence | |
| DOID:1596 | depressive disorder | |
| DOID:0050741 | alcohol dependence | |
| DOID:2559 | opiate dependence | |
| DOID:10024 | migraine with aura | |
| DOID:10763 | hypertension | |
| DOID:783 | end stage renal disease |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 13489 | MGI:94924 | |
| 24318 | RGD:2520 | |
| 179347 | WB:WBGene00001053 | |
| 33007 | FB:FBgn0053517 | |
| 378584 | Xenbase:XB-GENE-1005782 |
