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promyelocytic leukemia

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

18854

KEGG Gene ID

PubChem

18854

Alliance of Genome Resources

MGI:104662

Annotation

Keyword

Acetylation
Activator
Alternative splicing
Antiviral defense
Apoptosis
Biological rhythms
Coiled coil
Cytoplasm
DNA-binding
Endoplasmic reticulum
Endosome
Host-virus interaction
Innate immunity
Isopeptide bond
Membrane
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Transcription regulation
Tumor suppressor
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 4** entries
UniProt	Protein Name
D3Z3A6
Q8BSJ6
Q60953
A0A068EW80

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of **117** in total

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GO Term	Evidence Code	PMID
response to hypoxia	ISS
response to hypoxia	ISO
response to hypoxia	IMP
response to hypoxia	IEA
positive regulation of defense response to virus by host	ISO

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

innate immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

extrinsic apoptotic signaling pathway

hormone-mediated signaling pathway [inference]

retinoic acid receptor signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

nuclear receptor-mediated signaling pathway [inference]

retinoic acid receptor signaling pathway

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intracellular signaling cassette [inference]

SMAD protein signal transduction

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

cell death [inference]

programmed cell death [inference]

apoptotic process

intercellular transport [inference]

import into nucleus [inference]

protein import into nucleus

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation

cell fate commitment

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

fibroblast migration

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

response to endoplasmic reticulum stress [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin remodeling

organelle organization [inference]

nucleus organization [inference]

nuclear body organization [inference]

PML body organization

cellular component assembly [inference]

protein-containing complex assembly

protein-containing complex organization [inference]

protein-containing complex assembly

cellular senescence

oncogene-induced cell senescence

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube [inference]

branching involved in mammary gland duct morphogenesis

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation

cell fate commitment

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

endoplasmic reticulum calcium ion homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

suppression of viral release by host

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

rhythmic process

circadian rhythm [inference]

circadian regulation of gene expression

response to stimulus [inference]

response to stress [inference]

response to hypoxia

defense response [inference]

defense response to virus [inference]

suppression of viral release by host

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

response to endoplasmic reticulum stress [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

immune response [inference]

innate immune response

response to external stimulus [inference]

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

suppression of viral release by host

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus [inference]

suppression of viral release by host

defense response to other organism [inference]

defense response to symbiont [inference]

innate immune response

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV

photoperiodism [inference]

entrainment of circadian clock by photoperiod

response to ionizing radiation [inference]

response to gamma radiation

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to chemical [inference]

response to peptide [inference]

response to cytokine

response to interleukin-4 [inference]

cellular response to interleukin-4

cellular response to cytokine stimulus [inference]

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

response to endoplasmic reticulum stress [inference]

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

protein localization to organelle [inference]

protein localization to nucleus

protein import into nucleus

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

import into nucleus [inference]

protein import into nucleus

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

establishment of protein localization

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein location in nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport [inference]

import into nucleus [inference]

protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to chromosome, telomeric region

regulation of protein localization to chromosome, telomeric region [inference]

positive regulation of protein localization to chromosome, telomeric region

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of calcium ion transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol

regulation of cellular localization

regulation of calcium ion transport into cytosol

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth

negative regulation of growth [inference]

negative regulation of cell growth

regulation of circadian rhythm

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of developmental process [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of protein localization [inference]

positive regulation of protein localization to chromosome, telomeric region

negative regulation of biological process [inference]

negative regulation of growth [inference]

negative regulation of cell growth

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of cell growth

negative regulation of cell cycle [inference]

negative regulation of mitotic cell cycle

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host [inference]

positive regulation of defense response to virus by host

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

regulation of response to external stimulus [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host [inference]

positive regulation of defense response to virus by host

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host [inference]

positive regulation of defense response to virus by host

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

regulation of double-strand break repair

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

positive regulation of developmental process [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

extrinsic apoptotic signaling pathway

hormone-mediated signaling pathway [inference]

retinoic acid receptor signaling pathway

intracellular signal transduction [inference]

intracellular receptor signaling pathway [inference]

nuclear receptor-mediated signaling pathway [inference]

retinoic acid receptor signaling pathway

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intracellular signaling cassette [inference]

SMAD protein signal transduction

apoptotic signaling pathway [inference]

extrinsic apoptotic signaling pathway

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of intracellular signal transduction [inference]

regulation of signal transduction by p53 class mediator [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

regulation of transcription, DNA-templated

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation [inference]

regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

regulation of translation in response to stress [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

circadian regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

regulation of MHC class I biosynthetic process

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of catabolic process [inference]

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

regulation of transcription, DNA-templated

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation [inference]

regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

regulation of translation in response to stress [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

circadian regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

regulation of MHC class I biosynthetic process

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of DNA metabolic process [inference]

regulation of DNA repair [inference]

regulation of double-strand break repair

regulation of telomere maintenance [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

positive regulation of telomere maintenance

regulation of telomere maintenance via telomere lengthening [inference]

regulation of telomere maintenance via telomerase [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

regulation of protein metabolic process

regulation of translation [inference]

regulation of translational initiation [inference]

regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

regulation of translation in response to stress [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

regulation of protein acetylation [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

regulation of peptidyl-lysine acetylation [inference]

positive regulation of peptidyl-lysine acetylation

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

regulation of DNA metabolic process [inference]

regulation of DNA repair [inference]

regulation of double-strand break repair

regulation of telomere maintenance [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

positive regulation of telomere maintenance

regulation of telomere maintenance via telomere lengthening [inference]

regulation of telomere maintenance via telomerase [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

regulation of DNA biosynthetic process [inference]

regulation of telomere maintenance via telomerase [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of protein metabolic process

regulation of translation [inference]

regulation of translational initiation [inference]

regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

regulation of translation in response to stress [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

regulation of protein modification process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

regulation of protein acetylation [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

regulation of peptidyl-lysine acetylation [inference]

positive regulation of peptidyl-lysine acetylation

regulation of protein catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

regulation of cell adhesion

regulation of transmembrane transport [inference]

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of calcium ion transmembrane transport [inference]

regulation of calcium ion transport into cytosol

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

negative regulation of cell population proliferation

regulation of fibroblast proliferation [inference]

positive regulation of fibroblast proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

regulation of apoptotic signaling pathway [inference]

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

regulation of extrinsic apoptotic signaling pathway [inference]

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of fibroblast proliferation

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of DNA metabolic process [inference]

positive regulation of telomere maintenance

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein acetylation [inference]

positive regulation of peptidyl-lysine acetylation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of signal transduction by p53 class mediator

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process [inference]

positive regulation of apoptotic process involved in development [inference]

positive regulation of apoptotic process involved in morphogenesis [inference]

positive regulation of apoptotic process involved in mammary gland involution

positive regulation of apoptotic signaling pathway

positive regulation of extrinsic apoptotic signaling pathway

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of catabolic process [inference]

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of protein metabolic process [inference]

negative regulation of translation [inference]

negative regulation of translation in response to stress [inference]

regulation of translation in response to oxidative stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of translational initiation [inference]

negative regulation of translational initiation in response to stress [inference]

negative regulation of translation in response to oxidative stress

negative regulation of protein catabolic process [inference]

negative regulation of ubiquitin-dependent protein catabolic process

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of DNA biosynthetic process [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription

negative regulation of cell growth

negative regulation of cell cycle [inference]

negative regulation of mitotic cell cycle

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

regulation of chromosome organization [inference]

regulation of telomere maintenance [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

positive regulation of telomere maintenance

regulation of telomere maintenance via telomere lengthening [inference]

regulation of telomere maintenance via telomerase [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of chromosome organization [inference]

negative regulation of telomere maintenance [inference]

negative regulation of telomere maintenance via telomere lengthening [inference]

negative regulation of telomere maintenance via telomerase

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of chromosome organization [inference]

positive regulation of telomere maintenance

regulation of cell cycle

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle

negative regulation of cell cycle [inference]

negative regulation of mitotic cell cycle

regulation of cellular localization

regulation of calcium ion transport into cytosol

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

regulation of double-strand break repair

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

regulation of interleukin-1 production [inference]

regulation of interleukin-1 beta production [inference]

negative regulation of interleukin-1 beta production

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of interleukin-1 production

negative regulation of interleukin-1 beta production

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of biological quality [inference]

regulation of calcium ion transport into cytosol

regulation of protein stability [inference]

protein stabilization

Displaying entries **1 - 5** of 29 in total

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GO Term	Evidence Code	PMID
chromosome, telomeric region	ISO
chromosome, telomeric region	IEA
nucleus	ISO
nucleus	IDA
nucleus	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

early endosome membrane

nuclear membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

early endosome membrane

nuclear matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

nuclear body

PML body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nucleolus

nuclear body

PML body

chromosomal region [inference]

chromosome, telomeric region

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
DNA binding
transcription coactivator activity	ISO
transcription coactivator activity	TAS
protein binding	IPI
zinc ion binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

binding [inference]

nucleic acid binding [inference]

DNA binding

protein binding

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

ubiquitin-like protein binding [inference]

SUMO binding

identical protein binding

protein homodimerization activity

SMAD binding

protein dimerization activity [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

molecular adaptor activity

transcription regulator activity [inference]

transcription coregulator activity [inference]

transcription coactivator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

three prime repair exonuclease

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements