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proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

Summary

Gene Symbol

Psme1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19186

PubChem

19186

Alliance of Genome Resources

MGI:1096367

Annotation

Keyword

3D-structure
Proteasome
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P97371	11S regulator complex subunit alpha Activator of multicatalytic protease subunit 1 Proteasome activator 28 subunit alpha
Q5HZK3	11S regulator complex subunit alpha Activator of multicatalytic protease subunit 1 Proteasome activator 28 subunit alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
antigen processing and presentation of exogenous antigen	IMP	15944286
antigen processing and presentation of exogenous antigen	IEA	http://purl.obolibrary.org/obo/go/references/0000117
regulation of proteasomal protein catabolic process	ISO	http://purl.obolibrary.org/obo/go/references/0000119
regulation of proteasomal protein catabolic process	IBA	http://purl.obolibrary.org/obo/go/references/0000033
regulation of proteasomal protein catabolic process	IEA	http://purl.obolibrary.org/obo/go/references/0000107

GO Hierarchy

biological process

immune system process [inference]

antigen processing and presentation [inference]

antigen processing and presentation of exogenous antigen

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of protein catabolic process [inference]

regulation of proteasomal protein catabolic process

regulation of macromolecule metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

regulation of proteasomal protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

regulation of proteasomal protein catabolic process

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle process [inference]

regulation of cell cycle phase transition [inference]

regulation of mitotic cell cycle phase transition [inference]

regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle G1/S phase transition [inference]

regulation of G1/S transition of mitotic cell cycle

Displaying **all 4** entries
GO Term	Evidence Code	PMID
proteasome complex	ISO
nucleoplasm	IBA	http://purl.obolibrary.org/obo/go/references/0000033
cytoplasm
proteasome activator complex	IEA	http://purl.obolibrary.org/obo/go/references/0000002

GO Hierarchy

cellular component

protein-containing complex [inference]

proteasome activator complex

intracellular protein-containing complex [inference]

proteasome complex

catalytic complex [inference]

peptidase complex [inference]

endopeptidase complex [inference]

proteasome complex

cellular anatomical structure [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	15944286
endopeptidase activator activity	IDA	15944286

GO Hierarchy

molecular function

binding [inference]

protein binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

peptidase activator activity [inference]

endopeptidase activator activity

peptidase regulator activity [inference]

peptidase activator activity [inference]

endopeptidase activator activity

endopeptidase regulator activity [inference]

endopeptidase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

peptidase activator activity [inference]

endopeptidase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

proteasome activator

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
endopeptidase activator activity
regulation of G1/S transition of mitotic cell cycle
regulation of proteasomal protein catabolic process

Displaying **all 6** entries
InterPro
Proteasome activator PA28, C-terminal domain superfamily
Proteasome activator PA28, C-terminal domain
Proteasome activator PA28, N-terminal domain superfamily
Proteasome activator PA28, N-terminal domain
Proteasome activator PA28
Proteasome activator superfamily