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MIRAGE
patched 1
Summary
- Gene Symbol
-
- Ptch1
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| negative regulation of transcription by RNA polymerase II |
|
|
| branching involved in ureteric bud morphogenesis |
|
|
| in utero embryonic development |
|
|
| cell fate determination |
|
GO Hierarchy
- signal transduction
biological process
cellular process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of cell differentiation [inference]
negative regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| Golgi apparatus |
|
|
| Golgi apparatus |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| patched binding |
|
|
| smoothened binding |
|
|
| smoothened binding |
|
|
| smoothened binding |
|
|
| protein binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- patched
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| hedgehog family protein binding |
| hedgehog receptor activity |
| smoothened binding |
| InterPro |
|---|
| Protein patched/dispatched |
| Sterol-sensing domain |
| Transmembrane receptor, patched |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050902 | medulloblastoma | |
| DOID:2513 | basal cell carcinoma | |
| DOID:2512 | nevoid basal cell carcinoma syndrome |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 174274 | WB:WBGene00004208 | |
| 173631 | WB:WBGene00004210 | |
| 35851 | FB:FBgn0003892 | |
| 5727 | HGNC:9585 |
