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prostaglandin E receptor 2 (subtype EP2)

Summary

Gene Symbol

Ptger2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19217

PubChem

19217

Alliance of Genome Resources

MGI:97794

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q62053	Prostanoid EP2 receptor
Q543A9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
inflammatory response	IBA
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IDA	18403039
adenylate cyclase-activating G protein-coupled receptor signaling pathway	IBA
positive regulation of cytosolic calcium ion concentration	IBA
response to nematode	IMP	32484881

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-33 production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-33 production

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-33 production

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-33 production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-33 production

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

interleukin-33 production

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

multicellular organismal process [inference]

cytokine production [inference]

interleukin-33 production

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to nematode

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to nematode

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to nematode

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to prostaglandin [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to steroid hormone [inference]

response to progesterone

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to prostaglandin [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to steroid hormone [inference]

response to progesterone

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to progesterone

response to lipid [inference]

response to lipopolysaccharide

response to prostaglandin [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

response to steroid hormone [inference]

response to progesterone

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

response to alcohol [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

response to ketone [inference]

response to progesterone

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

response to oxygen-containing compound [inference]

response to lipopolysaccharide

response to alcohol [inference]

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

response to ketone [inference]

response to progesterone

response to prostaglandin E [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to lipid [inference]

cellular response to prostaglandin stimulus [inference]

cellular response to prostaglandin E stimulus

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to oxygen-containing compound [inference]

cellular response to alcohol [inference]

cellular response to prostaglandin E stimulus

cellular response to ketone [inference]

cellular response to prostaglandin E stimulus

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of blood circulation [inference]

positive regulation of gastric mucosal blood circulation

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cell population proliferation

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

positive regulation of blood circulation [inference]

positive regulation of gastric mucosal blood circulation

regulation of gastric mucosal blood circulation [inference]

positive regulation of gastric mucosal blood circulation

positive regulation of multicellular organismal process [inference]

positive regulation of blood circulation [inference]

positive regulation of gastric mucosal blood circulation

regulation of biological quality [inference]

positive regulation of cytosolic calcium ion concentration

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
prostaglandin E receptor activity	ISO
prostaglandin E receptor activity	IBA
prostaglandin E receptor activity	IEA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

icosanoid receptor activity [inference]

prostanoid receptor activity [inference]

prostaglandin receptor activity [inference]

prostaglandin E receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

prostaglandin e2 receptor ep3 subtype

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
inflammatory response
positive regulation of cytosolic calcium ion concentration

Displaying **all 3** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Prostanoid receptor

Ortholog

Displaying entries **41 - 50** of 88 in total

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Species	Gene ID	Orthologous MAtrix
Cricetulus griseus	100774710	CRIGR22578
Otolemur garnettii	100965094	OTOGA10067
Pan paniscus	100969154	PANPA11978
Papio anubis	101013953	PAPAN37714
Papio anubis	101014300	PAPAN37714
Felis catus	101098059	FELCA14802
Gorilla gorilla gorilla	101150673	GORGO08356
Tursiops truncatus	101332678	TURTR01199
Octodon degus	101567660	OCTDE16570
Jaculus jaculus	101597635	JACJA00104