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Guidelines

MIRAGE

protein tyrosine phosphatase receptor type B

Summary

Gene Symbol

Ptprb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19263

KEGG Gene ID

PubChem

19263

Alliance of Genome Resources

MGI:97809

Annotation

Keyword

Angiogenesis
Glycoprotein
Phosphoprotein
Protein phosphatase
Proteomics identification
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B2RU80	Vascular endothelial protein tyrosine phosphatase
A0A1W2P7W3	Vascular endothelial protein tyrosine phosphatase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
angiogenesis	ISO
angiogenesis	IDA
angiogenesis	IMP
angiogenesis	IBA
angiogenesis	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

cell motility [inference]

cell migration [inference]

glial cell migration

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

cellular developmental process [inference]

cell differentiation [inference]

osteoblast differentiation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of cellular process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IEA
signaling receptor complex	ISO
signaling receptor complex	IBA
signaling receptor complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

cellular anatomical structure [inference]

membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity	IDA
protein tyrosine phosphatase activity	IEA
protein binding	IPI
transmembrane receptor protein tyrosine kinase inhibitor activity	ISO
transmembrane receptor protein tyrosine kinase inhibitor activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

binding [inference]

protein binding

cell adhesion molecule binding [inference]

cadherin binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

kinase inhibitor activity [inference]

protein kinase inhibitor activity [inference]

protein tyrosine kinase inhibitor activity [inference]

transmembrane receptor protein tyrosine kinase inhibitor activity

kinase regulator activity [inference]

kinase inhibitor activity [inference]

protein kinase inhibitor activity [inference]

protein tyrosine kinase inhibitor activity [inference]

transmembrane receptor protein tyrosine kinase inhibitor activity

protein kinase regulator activity [inference]

protein kinase inhibitor activity [inference]

protein tyrosine kinase inhibitor activity [inference]

transmembrane receptor protein tyrosine kinase inhibitor activity

signaling receptor regulator activity [inference]

signaling receptor inhibitor activity [inference]

transmembrane receptor protein tyrosine kinase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

kinase inhibitor activity [inference]

protein kinase inhibitor activity [inference]

protein tyrosine kinase inhibitor activity [inference]

transmembrane receptor protein tyrosine kinase inhibitor activity

signaling receptor inhibitor activity [inference]

transmembrane receptor protein tyrosine kinase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	174437	WB:WBGene00009717
Drosophila melanogaster	32115	FB:FBgn0004370
Homo sapiens	5787	HGNC:9665

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026