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RAB4B, member RAS oncogene family

Summary

Gene Symbol

Rab4b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19342

KEGG Gene ID

PubChem

19342

Alliance of Genome Resources

MGI:105071

Annotation

Keyword

Acetylation
Cell membrane
Endosome
GTP-binding
Hydrolase
Magnesium
Membrane
Metal-binding
Methylation
Phosphoprotein
Prenylation
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q91ZR1
Q4V9W8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
protein transport
vesicle-mediated transport	IBA
regulation of endocytosis	IBA
Rab protein signal transduction	IEA
endosomal vesicle fusion	ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction [inference]

Rab protein signal transduction

intercellular transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

Golgi vesicle transport [inference]

early endosome to Golgi transport

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

D-glucose transmembrane transport [inference]

D-glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle fusion [inference]

endosomal vesicle fusion

organelle fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

membrane organization [inference]

membrane fusion [inference]

organelle membrane fusion [inference]

vesicle fusion [inference]

endosomal vesicle fusion

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

carbohydrate transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

D-glucose transmembrane transport [inference]

D-glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

intercellular transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

protein transport

vesicle-mediated transport

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

Golgi vesicle transport [inference]

early endosome to Golgi transport

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

transmembrane transport [inference]

carbohydrate transmembrane transport [inference]

monosaccharide transmembrane transport [inference]

hexose transmembrane transport [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

D-glucose transmembrane transport [inference]

D-glucose import across plasma membrane

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

import into cell [inference]

import across plasma membrane [inference]

carbohydrate import across plasma membrane [inference]

hexose import across plasma membrane [inference]

D-glucose import across plasma membrane

establishment of protein localization [inference]

protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi [inference]

early endosome to Golgi transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

intracellular signaling cassette [inference]

small GTPase-mediated signal transduction [inference]

Rab protein signal transduction

regulation of cellular component organization [inference]

regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

Displaying entries **6 - 10** of 17 in total

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GO Term	Evidence Code	PMID
synaptic vesicle membrane	ISO
early endosome membrane	ISS
early endosome membrane	ISO
early endosome membrane	IEA
insulin-responsive compartment	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytosol

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

endosome membrane [inference]

early endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

early endosome membrane

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

secretory vesicle [inference]

secretory granule [inference]

insulin-responsive compartment

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

secretory vesicle [inference]

secretory granule [inference]

insulin-responsive compartment

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

secretory vesicle [inference]

secretory granule [inference]

insulin-responsive compartment

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
GTPase activity	ISS
GTPase activity	ISO
GTPase activity	IBA
GTPase activity	IEA
G protein activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

G protein activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

molecular function regulator activity [inference]

G protein activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:19669

H₂O + GTP

H⁺ + phosphate + GDP

Enzyme

PMID

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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