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RAD1 checkpoint DNA exonuclease

Summary

Gene Symbol

Rad1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

19355

KEGG Gene ID

[""]

PubChem

19355

Alliance of Genome Resources

MGI:1316678

Annotation

Keyword

Alternative splicing
DNA repair
Nucleus
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9QWZ1	Rad1-like DNA damage checkpoint protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
DNA damage checkpoint signaling	ISO
DNA damage checkpoint signaling	IBA
DNA damage checkpoint signaling	IEA
DNA repair	IBA
meiotic recombination checkpoint signaling	ISO

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic recombination checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cell cycle process [inference]

meiotic cell cycle process [inference]

meiotic cell cycle checkpoint signaling [inference]

meiotic recombination checkpoint signaling

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

reproductive process [inference]

meiotic cell cycle process [inference]

meiotic cell cycle checkpoint signaling [inference]

meiotic recombination checkpoint signaling

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

response to abiotic stimulus [inference]

response to radiation [inference]

response to ionizing radiation [inference]

cellular response to ionizing radiation

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic recombination checkpoint signaling

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic recombination checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

negative regulation of cellular process [inference]

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic recombination checkpoint signaling

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

regulation of nuclear division [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic recombination checkpoint signaling

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic recombination checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

meiotic cell cycle checkpoint signaling [inference]

meiotic recombination checkpoint signaling

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division [inference]

meiotic recombination checkpoint signaling

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
nucleus	IEA
nucleoplasm	ISO
nucleoplasm	IEA
chromosome	ISO
chromosome	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

checkpoint clamp complex

cellular anatomical structure [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

chromosome

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

RAD1

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
3'-5' exonuclease activity
DNA repair

Displaying **all 2** entries
InterPro
DNA clamp superfamily
Rad1/Rec1/Rad17

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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Acknowledgements