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MIRAGE
C-C motif chemokine ligand 2
Summary
- Gene Symbol
-
- Ccl2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Chemotaxis
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Pyrrolidone carboxylic acid
- Reference proteome
- Secreted
- Signal
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis |
|
|
| response to hypoxia |
|
|
| positive regulation of leukocyte mediated cytotoxicity |
|
|
| positive regulation of leukocyte mediated cytotoxicity |
|
|
| positive regulation of endothelial cell proliferation |
|
GO Hierarchy
- response to activity
biological process
immune system process [inference]
cellular process [inference]
homeostatic process [inference]
response to stimulus [inference]
response to endogenous stimulus [inference]
response to chemical [inference]
cellular response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell cycle [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
|
| extracellular region |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled receptor binding |
|
|
| cytokine activity |
|
|
| protein binding |
|
|
| chemokine activity |
|
|
| chemokine activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- C-C motif chemokine 2
- Functional Category
-
- K: Transcription
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell chemotaxis |
| chemokine activity |
| cytokine activity |
| eosinophil chemotaxis |
| immune response |
| InterPro |
|---|
| Chemokine beta/gamma/delta |
| Chemokine interleukin-8-like domain |
| Chemokine interleukin-8-like superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10871 | age related macular degeneration |
