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selectin, endothelial cell

Summary

Gene Symbol

Sele

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

20339

PubChem

20339

Alliance of Genome Resources

MGI:98278

Annotation

Keyword

Calcium
Cell adhesion
Cell membrane
Disulfide bond
EGF-like domain
Glycoprotein
Lectin
Metal-binding
Proteomics identification
Reference proteome
Repeat
Signal
Sushi
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3U5F6	CD62 antigen-like family member E Endothelial leukocyte adhesion molecule 1 Leukocyte-endothelial cell adhesion molecule 2
Q00690	CD62 antigen-like family member E Endothelial leukocyte adhesion molecule 1 Leukocyte-endothelial cell adhesion molecule 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
positive regulation of receptor internalization	ISO
positive regulation of receptor internalization	IEA
positive regulation of leukocyte migration	IGI	17114491
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	ISO
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IBA

GO Hierarchy

biological process

immune system process [inference]

leukocyte migration

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

leukocyte cell-cell adhesion

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled receptor signaling pathway

actin filament-based process

cell motility [inference]

cell migration [inference]

leukocyte migration

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine

response to interleukin-1

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

positive regulation of receptor internalization

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

phospholipase C-activating G protein-coupled receptor signaling pathway

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

regulation of leukocyte adhesion to vascular endothelial cell [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cellular process [inference]

positive regulation of cell adhesion [inference]

positive regulation of cell-cell adhesion [inference]

positive regulation of leukocyte cell-cell adhesion [inference]

positive regulation of leukocyte adhesion to vascular endothelial cell [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

positive regulation of receptor internalization

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

positive regulation of receptor internalization

positive regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor internalization

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration

regulation of cellular extravasation [inference]

regulation of leukocyte tethering or rolling [inference]

positive regulation of leukocyte tethering or rolling

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IBA
extracellular space	IEA
plasma membrane	ISO
caveola	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

plasma membrane region [inference]

clathrin-coated pit

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft

plasma membrane raft [inference]

caveola

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

cortical cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

cortical cytoskeleton

perinuclear region of cytoplasm

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	ISO
transmembrane signaling receptor activity	IEA
calcium ion binding	IEA
sialic acid binding	ISO
sialic acid binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

enzyme binding [inference]

phospholipase binding

carbohydrate binding [inference]

oligosaccharide binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

sialic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

sialic acid binding

cation binding [inference]

metal ion binding [inference]

calcium ion binding

carbohydrate derivative binding [inference]

sialic acid binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

complement decay-accelerating factor

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Sushi/SCR/CCP domain
Sushi/SCR/CCP superfamily

Ortholog

Displaying entries **1 - 10** of 62 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6401	ZFIN:ZDB-GENE-041014-221	HUMAN53526
Danio rerio	20339	ZFIN:ZDB-GENE-041014-221
Rattus norvegicus	25544	ZFIN:ZDB-GENE-041014-221	RATNO06862
Danio rerio	29259	ZFIN:ZDB-GENE-041014-221
Danio rerio	32162	ZFIN:ZDB-GENE-041014-221
Danio rerio	188252	ZFIN:ZDB-GENE-041014-221
Bos taurus	281484		BOVIN08199
Sus scrofa	397508		PIGXX23524
Canis lupus familiaris	403999		CANLF17271
Ovis aries	443127		SHEEP03673