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ERCC excision repair 6, chromatin remodeling factor

Summary

Gene Symbol

ERCC6

Organism

Homo sapiens (human)

External Links

NCBI Gene

2074

KEGG Gene ID

PubChem

2074

Alliance of Genome Resources

HGNC:3438

Annotation

Keyword

3D-structure
Age-related macular degeneration
Alternative splicing
Cataract
Chromosome
Cockayne syndrome
DNA repair
DNA-binding
Deafness
Disease variant
Dwarfism
Helicase
Intellectual disability
Isopeptide bond
Methylation
Neurogenesis
Nucleus
Phosphoprotein
Premature ovarian failure
Proteomics identification
Reference proteome
Transcription regulation
Ubl conjugation
Xeroderma pigmentosum

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q59FF6	ATP-dependent helicase ERCC6 Cockayne syndrome protein CSB
Q03468	ATP-dependent helicase ERCC6 Cockayne syndrome protein CSB
P0DP91	Chimeric CSB-PGBD3 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 45 in total

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GO Term	Evidence Code	PMID
DNA repair	IEA
transcription-coupled nucleotide-excision repair	IDA
transcription-coupled nucleotide-excision repair	IMP
transcription-coupled nucleotide-excision repair	IBA
transcription-coupled nucleotide-excision repair	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

intracellular signaling cassette [inference]

MAPK cascade [inference]

JNK cascade

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase I

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase I

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase I

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

nucleotide-excision repair [inference]

transcription-coupled nucleotide-excision repair

pyrimidine dimer repair

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining [inference]

double-strand break repair via classical nonhomologous end joining

DNA protection

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase I

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase I

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase I

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

nucleotide-excision repair [inference]

transcription-coupled nucleotide-excision repair

pyrimidine dimer repair

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining [inference]

double-strand break repair via classical nonhomologous end joining

DNA protection

RNA metabolic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase I

nucleic acid biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription [inference]

transcription by RNA polymerase II

DNA-templated transcription elongation [inference]

transcription elongation by RNA polymerase I

cellular developmental process [inference]

cell differentiation [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

nucleotide-excision repair [inference]

transcription-coupled nucleotide-excision repair

pyrimidine dimer repair

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining [inference]

double-strand break repair via classical nonhomologous end joining

intrinsic apoptotic signaling pathway in response to DNA damage

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

DNA protection

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin remodeling

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

multicellular organismal process [inference]

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

growth [inference]

developmental growth [inference]

multicellular organism growth

response to stimulus [inference]

response to stress [inference]

response to oxidative stress

response to reactive oxygen species [inference]

response to oxygen radical [inference]

response to superoxide

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

nucleotide-excision repair [inference]

transcription-coupled nucleotide-excision repair

pyrimidine dimer repair

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining [inference]

double-strand break repair via classical nonhomologous end joining

intrinsic apoptotic signaling pathway in response to DNA damage

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

DNA protection

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

response to UV-B

response to ionizing radiation [inference]

response to chemical [inference]

response to toxic substance

response to oxygen-containing compound [inference]

response to reactive oxygen species [inference]

response to oxygen radical [inference]

response to superoxide

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

nucleotide-excision repair [inference]

transcription-coupled nucleotide-excision repair

pyrimidine dimer repair

double-strand break repair [inference]

double-strand break repair via nonhomologous end joining [inference]

double-strand break repair via classical nonhomologous end joining

intrinsic apoptotic signaling pathway in response to DNA damage

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

DNA protection

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromatin

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of response to stimulus [inference]

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

negative regulation of response to stimulus [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host [inference]

positive regulation of defense response to virus by host

regulation of response to external stimulus [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host [inference]

positive regulation of defense response to virus by host

positive regulation of response to stimulus [inference]

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

negative regulation of response to stimulus [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of defense response to virus [inference]

regulation of defense response to virus by host [inference]

positive regulation of defense response to virus by host

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

positive regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair via nonhomologous end joining [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

signal transduction in response to DNA damage [inference]

DNA damage checkpoint signaling

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

intracellular signaling cassette [inference]

MAPK cascade [inference]

JNK cascade

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription by RNA polymerase III [inference]

positive regulation of transcription by RNA polymerase III

regulation of DNA-templated transcription elongation

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription by RNA polymerase III [inference]

positive regulation of transcription by RNA polymerase III

regulation of DNA-templated transcription elongation

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation of STAT protein [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription by RNA polymerase III [inference]

positive regulation of transcription by RNA polymerase III

regulation of DNA-templated transcription elongation

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription by RNA polymerase III [inference]

positive regulation of transcription by RNA polymerase III

regulation of DNA-templated transcription elongation

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

positive regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair via nonhomologous end joining [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation of STAT protein [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription by RNA polymerase III [inference]

positive regulation of transcription by RNA polymerase III

regulation of DNA-templated transcription elongation

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

regulation of DNA metabolic process [inference]

regulation of DNA recombination [inference]

regulation of double-strand break repair via homologous recombination [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

positive regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair via nonhomologous end joining [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase I [inference]

positive regulation of transcription by RNA polymerase I

regulation of transcription by RNA polymerase II [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of transcription by RNA polymerase III [inference]

positive regulation of transcription by RNA polymerase III

regulation of DNA-templated transcription elongation

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of DNA-templated transcription initiation [inference]

regulation of transcription initiation by RNA polymerase II [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

regulation of peptidyl-serine phosphorylation of STAT protein [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of DNA metabolic process [inference]

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of DNA recombination [inference]

positive regulation of double-strand break repair via homologous recombination

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of DNA-templated transcription [inference]

positive regulation of transcription by RNA polymerase II

positive regulation of transcription initiation by RNA polymerase II

positive regulation of transcription by RNA polymerase III

positive regulation of DNA-templated transcription initiation [inference]

positive regulation of transcription initiation by RNA polymerase II

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation of STAT protein

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

cell cycle checkpoint signaling [inference]

DNA integrity checkpoint signaling [inference]

DNA damage checkpoint signaling

regulation of cellular response to stress [inference]

regulation of DNA repair [inference]

negative regulation of DNA repair [inference]

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of DNA repair

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair [inference]

regulation of double-strand break repair via homologous recombination [inference]

positive regulation of double-strand break repair via homologous recombination

negative regulation of double-strand break repair [inference]

negative regulation of double-strand break repair via nonhomologous end joining

positive regulation of double-strand break repair [inference]

positive regulation of double-strand break repair via homologous recombination

regulation of double-strand break repair via nonhomologous end joining [inference]

negative regulation of double-strand break repair via nonhomologous end joining

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
nucleus	IDA
nucleus	IBA
nucleus	IEA
nucleoplasm	TAS
nucleoplasm	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

nuclear protein-containing complex [inference]

transcription elongation factor complex

SWI/SNF superfamily-type complex [inference]

B-WICH complex

catalytic complex [inference]

ATPase complex [inference]

SWI/SNF superfamily-type complex [inference]

B-WICH complex

cellular anatomical structure [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

site of DNA damage

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
DNA binding	IDA
DNA helicase activity	IDA
chromatin binding	IDA
chromatin binding	IMP
helicase activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

isomerase activity [inference]

macromolecular conformation isomerase activity [inference]

nucleic acid conformation isomerase activity [inference]

helicase activity

DNA helicase activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity

DNA helicase activity

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA

binding [inference]

nucleic acid binding [inference]

DNA binding

sequence-specific DNA binding

chromatin binding

protein binding

enzyme binding [inference]

RNA polymerase binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

chromatin-protein adaptor activity

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

molecular sensor activity [inference]

DNA damage sensor activity [inference]

ATP-dependent DNA damage sensor activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein tyrosine kinase activator activity

ATP-dependent activity [inference]

helicase activity

DNA helicase activity

ATP-dependent activity, acting on DNA

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying entries **1 - 10** of 14 in total

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DO ID	Disease Name	Source
DOID:2596	larynx cancer	Alliance of Genome Resources
DOID:9256	colorectal cancer	Alliance of Genome Resources
DOID:2962	Cockayne syndrome	Alliance of Genome Resources
DOID:14184	polyneuropathy due to drug	Alliance of Genome Resources
DOID:0080199	colorectal carcinoma	Alliance of Genome Resources
DOID:0060240	UV-sensitive syndrome	Alliance of Genome Resources
DOID:10534	stomach cancer	Alliance of Genome Resources
DOID:1324	lung cancer	Alliance of Genome Resources
DOID:0080908	Cockayne syndrome B	Alliance of Genome Resources
DOID:0080911	cerebrooculofacioskeletal syndrome 1	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements