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Guidelines
MIRAGE
estrogen receptor 1
Summary
- Gene Symbol
-
- ESR1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Activator
- Alternative promoter usage
- Alternative splicing
- Cell membrane
- Cytoplasm
- DNA-binding
- Direct protein sequencing
- Disease variant
- Glycoprotein
- Golgi apparatus
- Methylation
- Nucleus
- Osteoporosis
- Palmitate
- Phosphoprotein
- Proteomics identification
- Receptor
- Reference proteome
- Steroid-binding
- Transcription regulation
- Transmembrane
- Ubl conjugation
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| P03372 |
|
| A0A125SXW3 |
|
| G4XH65 |
|
| A8KAF4 |
|
| Q9UBT1 |
|
| H0Y4W6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II |
|
|
| antral ovarian follicle growth |
|
|
| epithelial cell development |
|
|
| chromatin remodeling |
|
|
| regulation of transcription, DNA-templated |
|
GO Hierarchy
biological process
cellular process [inference]
reproductive process [inference]
developmental process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus |
|
|
| nucleus |
|
|
| nucleus |
|
|
| nucleoplasm |
|
|
| nucleoplasm |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II cis-regulatory region sequence-specific DNA binding |
|
|
| DNA-binding transcription factor activity, RNA polymerase II-specific |
|
|
| TFIIB-class transcription factor binding |
|
|
| transcription coregulator binding |
|
|
| transcription corepressor binding |
|
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:8029 | sporadic breast cancer | |
| DOID:2349 | arteriosclerosis | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:3459 | breast carcinoma | |
| DOID:4448 | macular degeneration | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:12306 | vitiligo | |
| DOID:289 | endometriosis | |
| DOID:8398 | osteoarthritis | |
| DOID:418 | systemic scleroderma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 13982 | MGI:1352467 | |
| 24890 | RGD:2581 |
