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rhodopsin

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

212541

KEGG Gene ID

PubChem

212541

Alliance of Genome Resources

MGI:97914

Annotation

Keyword

Acetylation
Cell projection
Disulfide bond
G-protein coupled receptor
Glycoprotein
Metal-binding
Palmitate
Phosphoprotein
Reference proteome
Retinal protein
Transmembrane helix
Vision
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
P15409

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 34 in total

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GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	IMP
protein phosphorylation	IDA
G protein-coupled receptor signaling pathway	ISO
G protein-coupled receptor signaling pathway	IBA
G protein-coupled receptor signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

phototransduction

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

light absorption [inference]

absorption of visible light

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

glutamatergic neuron differentiation [inference]

retinal bipolar neuron differentiation [inference]

rod bipolar cell differentiation

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

organelle assembly [inference]

membraneless organelle assembly [inference]

podosome assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

podosome assembly

organelle assembly [inference]

membraneless organelle assembly [inference]

podosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

podosome assembly

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus

visual perception

photoreceptor cell maintenance

developmental process [inference]

anatomical structure development [inference]

retina development in camera-type eye

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

glutamatergic neuron differentiation [inference]

retinal bipolar neuron differentiation [inference]

rod bipolar cell differentiation

locomotion [inference]

taxis [inference]

thermotaxis

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

detection of visible light [inference]

phototransduction, visible light

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

thermotaxis

response to radiation [inference]

response to light stimulus

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

detection of visible light [inference]

phototransduction, visible light

response to light intensity

cellular response to light stimulus

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

detection of abiotic stimulus [inference]

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

detection of visible light [inference]

phototransduction, visible light

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

detection of visible light [inference]

phototransduction, visible light

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

detection of abiotic stimulus [inference]

detection of light stimulus

phototransduction

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

detection of visible light [inference]

phototransduction, visible light

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

detection of stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

regulation of opsin-mediated signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of opsin-mediated signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

regulation of opsin-mediated signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

regulation of response to external stimulus [inference]

regulation of opsin-mediated signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of opsin-mediated signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

phototransduction

G protein-coupled opsin signaling pathway

transducin-mediated opsin signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

regulation of opsin-mediated signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of opsin-mediated signaling pathway

Displaying entries **1 - 5** of 29 in total

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GO Term	Evidence Code	PMID
photoreceptor outer segment	ISO
photoreceptor outer segment	IDA
photoreceptor outer segment	IBA
photoreceptor outer segment	IEA
photoreceptor inner segment	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane [inference]

rough endoplasmic reticulum membrane

photoreceptor disc membrane

bounding membrane of organelle [inference]

rough endoplasmic reticulum membrane

ciliary membrane [inference]

photoreceptor outer segment membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

sperm midpiece

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GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IEA
11-cis retinal binding	ISS
protein binding	IPI
G protein-coupled photoreceptor activity	ISS
G protein-coupled photoreceptor activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

spectrin binding

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinal binding

11-cis retinal binding

small molecule binding [inference]

vitamin binding [inference]

retinal binding

11-cis retinal binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

spectrin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled photoreceptor activity

photoreceptor activity [inference]

G protein-coupled photoreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Green-sensitive opsin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cellular response to light stimulus
metal ion binding
photoreceptor activity
phototransduction
visual perception

Displaying **all 6** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Opsin
Rhodopsin, N-terminal
Rhodopsin
Visual pigments (opsins) retinal binding site

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110372	retinitis pigmentosa 4	Alliance of Genome Resources
DOID:0110862	congenital stationary night blindness autosomal dominant 1	Alliance of Genome Resources

Ortholog

Displaying **all 5** entries
Species	Gene ID	Alliance of Genome Resources
Rattus norvegicus	24717	RGD:3573
Homo sapiens	6010	HGNC:10012
Danio rerio	30295	ZFIN:ZDB-GENE-990415-271
Danio rerio	562845	ZFIN:ZDB-GENE-070424-6
Xenopus tropicalis	100037900	Xenbase:XB-GENE-966887

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements