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cholinergic receptor, muscarinic 5

Summary

Gene Symbol

Chrm5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

213788

KEGG Gene ID

PubChem

213788

Alliance of Genome Resources

MGI:109248

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Postsynaptic cell membrane
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q920H4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
gastric acid secretion	IEA
G protein-coupled receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	IBA
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway	IBA
chemical synaptic transmission	IBA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

signal transduction [inference]

cell surface receptor signaling pathway [inference]

chemical synaptic transmission, postsynaptic

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

G protein-coupled acetylcholine receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

gastric acid secretion

nervous system process [inference]

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

organic hydroxy compound transport [inference]

catecholamine transport [inference]

dopamine transport

secretion [inference]

acid secretion [inference]

gastric acid secretion

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

nitrogen compound transport [inference]

monoamine transport [inference]

catecholamine transport [inference]

dopamine transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

chemical synaptic transmission, postsynaptic

G protein-coupled receptor signaling pathway

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

G protein-coupled acetylcholine receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway [inference]

G protein-coupled acetylcholine receptor signaling pathway [inference]

adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway

regulation of metabolic process [inference]

regulation of phosphorus metabolic process [inference]

regulation of dephosphorylation [inference]

regulation of phosphatidylinositol dephosphorylation

regulation of macromolecule metabolic process [inference]

regulation of phosphatidylinositol dephosphorylation

regulation of primary metabolic process [inference]

regulation of lipid metabolic process [inference]

regulation of phosphatidylinositol dephosphorylation

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of postsynaptic membrane potential [inference]

excitatory postsynaptic potential

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA
dendrite	IBA
synapse	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

Displaying **all 5** entries
GO Term	Evidence Code	PMID
G protein-coupled receptor activity	IEA
G protein-coupled acetylcholine receptor activity	ISO
G protein-coupled acetylcholine receptor activity	IBA
G protein-coupled acetylcholine receptor activity	IEA
extracellularly glycine-gated chloride channel activity	TAS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

extracellularly glycine-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glycine-gated chloride channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly glycine-gated ion channel activity [inference]

extracellularly glycine-gated chloride channel activity

inhibitory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly glycine-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glycine-gated chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

extracellularly glycine-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glycine-gated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity [inference]

extracellularly glycine-gated chloride channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity [inference]

extracellularly glycine-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glycine-gated chloride channel activity

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly glycine-gated ion channel activity [inference]

extracellularly glycine-gated chloride channel activity

inhibitory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly glycine-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glycine-gated chloride channel activity

gated channel activity [inference]

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

extracellular ligand-gated monoatomic ion channel activity [inference]

excitatory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly glycine-gated ion channel activity [inference]

extracellularly glycine-gated chloride channel activity

inhibitory extracellular ligand-gated monoatomic ion channel activity [inference]

extracellularly glycine-gated chloride channel activity

ligand-gated monoatomic anion channel activity [inference]

extracellularly glycine-gated chloride channel activity

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled amine receptor activity [inference]

G protein-coupled acetylcholine receptor activity

G protein-coupled neurotransmitter receptor activity [inference]

G protein-coupled acetylcholine receptor activity

acetylcholine receptor activity [inference]

G protein-coupled acetylcholine receptor activity

neurotransmitter receptor activity [inference]

postsynaptic neurotransmitter receptor activity [inference]

acetylcholine receptor activity [inference]

G protein-coupled acetylcholine receptor activity

G protein-coupled neurotransmitter receptor activity [inference]

G protein-coupled acetylcholine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

muscarinic acetylcholine receptor

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
G protein-coupled acetylcholine receptor signaling pathway
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway