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coagulation factor XIII A chain

Summary

Gene Symbol

F13A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

2162

KEGG Gene ID

PubChem

2162

Alliance of Genome Resources

HGNC:3531

Annotation

Keyword

3D-structure
Acetylation
Acyltransferase
Blood coagulation
Calcium
Cytoplasm
Direct protein sequencing
Disease variant
Glycoprotein
Metal-binding
Proteomics identification
Reference proteome
Secreted
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
P00488	Protein-glutamine gamma-glutamyltransferase A chain Transglutaminase A chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
blood coagulation	TAS
peptide cross-linking	IDA
peptide cross-linking	IBA
blood coagulation, fibrin clot formation	IDA
blood coagulation, fibrin clot formation	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, fibrin clot formation

macromolecule modification [inference]

protein modification process [inference]

peptide cross-linking

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

peptide cross-linking

protein maturation [inference]

protein activation cascade [inference]

blood coagulation, fibrin clot formation

multicellular organismal process [inference]

coagulation [inference]

blood coagulation

biological regulation [inference]

regulation of biological quality [inference]

regulation of body fluid levels [inference]

hemostasis [inference]

blood coagulation

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GO Term	Evidence Code	PMID
extracellular region	EXP
extracellular region	NAS
extracellular region	TAS
extracellular region	IEA
obsolete extracellular space

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

transferase complex

cellular anatomical structure [inference]

external encapsulating structure [inference]

extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

platelet alpha granule lumen

intracellular organelle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

platelet alpha granule lumen

blood microparticle

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein-glutamine gamma-glutamyltransferase activity	TAS
protein-glutamine gamma-glutamyltransferase activity	IDA
protein-glutamine gamma-glutamyltransferase activity	IBA
protein-glutamine gamma-glutamyltransferase activity	IEA
protein binding	IPI

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

protein-glutamine gamma-glutamyltransferase activity

catalytic activity, acting on a protein [inference]

protein-glutamine gamma-glutamyltransferase activity

binding [inference]

protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

transglutaminase

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 2** entries
Gene Ontology
metal ion binding
protein-glutamine gamma-glutamyltransferase activity

Displaying **all 9** entries
InterPro
Immunoglobulin E-set
Immunoglobulin-like fold
Papain-like cysteine peptidase superfamily
Protein-glutamine gamma-glutamyltransferase, animal
Transglutaminase, C-terminal domain superfamily
Transglutaminase, C-terminal
Transglutaminase, N-terminal
Transglutaminase-like superfamily
Transglutaminase-like

Disease

Disease Ontology

Displaying **all 7** entries
DO ID	Disease Name	Source
DOID:9477	pulmonary embolism	Alliance of Genome Resources
DOID:9286	priapism	Alliance of Genome Resources
DOID:11247	disseminated intravascular coagulation	Alliance of Genome Resources
DOID:0111907	thrombophilia due to thrombin defect	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:2211	factor XIII deficiency	Alliance of Genome Resources
DOID:2349	arteriosclerosis	Alliance of Genome Resources

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	74145	MGI:1921395
Rattus norvegicus	60327	RGD:621495

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements