GlyCosmos Portal

Submissions

TEK receptor tyrosine kinase

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

21687

PubChem

21687

Alliance of Genome Resources

MGI:98664

Annotation

Keyword

ATP-binding
Cell junction
Cell membrane
Cytoskeleton
Disulfide bond
EGF-like domain
Glycoprotein
Immunoglobulin domain
Magnesium
Metal-binding
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix
Tyrosine-protein kinase
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q80YS4	Endothelial tyrosine kinase Tunica interna endothelial cell kinase Tyrosine kinase with Ig and EGF homology domains-2 Tyrosine-protein kinase receptor TEK Tyrosine-protein kinase receptor TIE-2 p140 TEK
Q02858	Endothelial tyrosine kinase HYK STK1 Tunica interna endothelial cell kinase Tyrosine kinase with Ig and EGF homology domains-2 Tyrosine-protein kinase receptor TEK Tyrosine-protein kinase receptor TIE-2 p140 TEK
B1AWS8	Endothelial tyrosine kinase Tunica interna endothelial cell kinase Tyrosine kinase with Ig and EGF homology domains-2 Tyrosine-protein kinase receptor TEK Tyrosine-protein kinase receptor TIE-2 p140 TEK

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 94 in total

1

2

3

4

5

…

Next ›

Last »
GO Term	Evidence Code	PMID
angiogenesis	ISO	http://purl.obolibrary.org/obo/go/references/0000119
angiogenesis	TAS	20299672
angiogenesis	IMP	7596437 9846489
angiogenesis	IBA	http://purl.obolibrary.org/obo/go/references/0000033
angiogenesis	IEA	http://purl.obolibrary.org/obo/go/references/0000117

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion

cell-cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

Tie signaling pathway

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

peptidyl-tyrosine phosphorylation

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-tyrosine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-tyrosine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

peptidyl-tyrosine phosphorylation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine phosphorylation

cell population proliferation [inference]

epithelial cell proliferation [inference]

endothelial cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

vasculogenesis

cell development [inference]

hemopoiesis

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

multicellular organismal process [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in blood vessel morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

morphogenesis of a branching structure [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in blood vessel morphogenesis

tube morphogenesis [inference]

branching morphogenesis of an epithelial tube

branching involved in blood vessel morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of a branching epithelium [inference]

branching morphogenesis of an epithelial tube

branching involved in blood vessel morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

sprouting angiogenesis

trabecula formation [inference]

heart trabecula formation

anatomical structure development [inference]

blood vessel development [inference]

glomerulus vasculature development

cell development [inference]

hemopoiesis

animal organ development [inference]

heart development

system development [inference]

vasculature development [inference]

renal system vasculature development [inference]

kidney vasculature development [inference]

glomerulus vasculature development

cellular developmental process [inference]

cell differentiation [inference]

vasculogenesis

cell development [inference]

hemopoiesis

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to endogenous stimulus [inference]

response to hormone [inference]

response to estrogen

response to chemical [inference]

response to hormone [inference]

response to estrogen

response to lipid [inference]

response to retinoic acid

response to oxygen-containing compound [inference]

response to retinoic acid

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

positive regulation of vascular endothelial growth factor receptor signaling pathway

regulation of intracellular signal transduction

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of small GTPase mediated signal transduction [inference]

regulation of Rac protein signal transduction [inference]

positive regulation of Rac protein signal transduction

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

regulation of protein localization to nucleus [inference]

regulation of protein import into nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of protein localization to nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of protein localization to nucleus [inference]

positive regulation of protein import into nucleus

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

regulation of cell motility [inference]

regulation of cell migration

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of signaling [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of cell communication [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell adhesion

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

positive regulation of cellular component organization [inference]

positive regulation of cell-substrate junction organization [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of protein localization to nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of endothelial cell apoptotic process

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

positive regulation of vascular endothelial growth factor receptor signaling pathway

regulation of intracellular signal transduction

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of small GTPase mediated signal transduction [inference]

regulation of Rac protein signal transduction [inference]

positive regulation of Rac protein signal transduction

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cellular response to growth factor stimulus [inference]

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

positive regulation of vascular endothelial growth factor receptor signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

positive regulation of developmental process [inference]

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway

Tie signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of vascular endothelial growth factor receptor signaling pathway [inference]

positive regulation of vascular endothelial growth factor receptor signaling pathway

regulation of intracellular signal transduction

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

regulation of ERK1 and ERK2 cascade [inference]

positive regulation of ERK1 and ERK2 cascade

regulation of small GTPase mediated signal transduction [inference]

regulation of Rac protein signal transduction [inference]

positive regulation of Rac protein signal transduction

regulation of Rho protein signal transduction [inference]

positive regulation of Rho protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of non-canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

regulation of peptidyl-serine phosphorylation [inference]

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

regulation of cell adhesion [inference]

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

regulation of focal adhesion assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

positive regulation of cell adhesion

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

regulation of establishment or maintenance of cell polarity

regulation of cell population proliferation [inference]

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of endothelial cell apoptotic process

regulation of endothelial cell apoptotic process

negative regulation of endothelial cell apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of endothelial cell apoptotic process

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

regulation of cell junction assembly [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation

positive regulation of peptidyl-serine phosphorylation

positive regulation of cell communication [inference]

positive regulation of signal transduction

positive regulation of vascular endothelial growth factor receptor signaling pathway

positive regulation of intracellular signal transduction

positive regulation of MAPK cascade

positive regulation of ERK1 and ERK2 cascade

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell adhesion

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion [inference]

positive regulation of focal adhesion assembly

positive regulation of cellular component organization [inference]

positive regulation of cell-substrate junction organization [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of endothelial cell apoptotic process

regulation of cellular component organization [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell-substrate junction organization [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

regulation of cell-substrate junction organization [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell-substrate junction organization [inference]

positive regulation of focal adhesion assembly

regulation of cell junction assembly [inference]

regulation of cell-substrate junction assembly [inference]

regulation of focal adhesion assembly [inference]

positive regulation of focal adhesion assembly

positive regulation of cell junction assembly [inference]

positive regulation of focal adhesion assembly

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of intracellular protein transport [inference]

positive regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus [inference]

positive regulation of protein import into nucleus

positive regulation of nucleocytoplasmic transport [inference]

positive regulation of protein import into nucleus

regulation of cell motility [inference]

regulation of cell migration

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of endothelial cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response

positive regulation of multicellular organismal process

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

Displaying entries **1 - 5** of 31 in total

1

2

3

4

5

…

Next ›

Last »
GO Term	Evidence Code	PMID
stress fiber	ISO
stress fiber	IEA	http://purl.obolibrary.org/obo/go/references/0000107
extracellular region	ISO	http://purl.obolibrary.org/obo/go/references/0000119
extracellular region	IEA	http://purl.obolibrary.org/obo/go/references/0000044
centrosome	ISO	http://purl.obolibrary.org/obo/go/references/0000119

GO Hierarchy

cellular component

protein-containing complex [inference]

signaling receptor complex

cellular anatomical structure [inference]

extracellular region

microtubule organizing center [inference]

cell surface

membrane

plasma membrane

plasma membrane region [inference]

membrane microdomain [inference]

membrane raft

cell junction [inference]

anchoring junction

cell-cell junction

cell-substrate junction [inference]

focal adhesion

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

perinuclear region of cytoplasm

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

actin filament

Displaying entries **1 - 5** of 17 in total

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
protein kinase activity	IEA
protein tyrosine kinase activity	ISO	http://purl.obolibrary.org/obo/go/references/0000119
protein tyrosine kinase activity	TAS	https://reactome.org/content/detail/R-MMU-211119
protein tyrosine kinase activity	IDA	7958865
protein tyrosine kinase activity	IEA	http://purl.obolibrary.org/obo/go/references/0000002 http://purl.obolibrary.org/obo/go/references/0000116 http://purl.obolibrary.org/obo/go/references/0000117

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity

transmembrane receptor protein tyrosine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity

transmembrane receptor protein tyrosine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity

transmembrane receptor protein tyrosine kinase activity

binding [inference]

protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity

transmembrane receptor protein tyrosine kinase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tyrosine-protein kinase receptor tie-1

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
nucleotide binding
positive regulation of angiogenesis
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway

Displaying entries **1 - 10** of 12 in total

1

2

Next ›

Last »
InterPro
EGF-like domain
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements