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nucleoporin 153

Summary

Gene Symbol

Nup153

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

218210

KEGG Gene ID

PubChem

218210

Alliance of Genome Resources

MGI:2385621

Annotation

Keyword

DNA-binding
Isopeptide bond
Membrane
Nuclear pore complex
Nucleus
Reference proteome
Repeat
Transport
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q8BRF6	153 kDa nucleoporin Nucleoporin Nup153
E9Q3G8	153 kDa nucleoporin Nucleoporin Nup153
Q3V3W1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
RNA export from nucleus	IBA
protein import into nucleus	IBA
nucleocytoplasmic transport	NAS
protein transport
negative regulation of RNA export from nucleus	ISO

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

amyloid fibril formation

primary metabolic process [inference]

protein metabolic process [inference]

amyloid fibril formation

intercellular transport [inference]

nuclear export [inference]

RNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

nucleus organization [inference]

nuclear pore organization [inference]

nuclear pore complex assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

pore complex assembly [inference]

nuclear pore complex assembly

protein-containing complex organization [inference]

nuclear pore organization [inference]

nuclear pore complex assembly

protein-containing complex assembly [inference]

pore complex assembly [inference]

nuclear pore complex assembly

supramolecular fiber organization [inference]

amyloid fibril formation

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

intercellular transport [inference]

nuclear export [inference]

RNA export from nucleus

import into nucleus [inference]

protein import into nucleus

protein transport

intracellular protein transport [inference]

protein import into nucleus

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus

import into nucleus [inference]

protein import into nucleus

nitrogen compound transport [inference]

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

establishment of protein localization [inference]

protein transport

intracellular protein transport [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus

import into nucleus [inference]

protein import into nucleus

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein import into nucleus

nuclear transport [inference]

nucleocytoplasmic transport

nuclear export [inference]

RNA export from nucleus

import into nucleus [inference]

protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of nucleobase-containing compound transport [inference]

negative regulation of nucleobase-containing compound transport [inference]

negative regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

negative regulation of RNA export from nucleus

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

regulation of nucleocytoplasmic transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

negative regulation of RNA export from nucleus

negative regulation of transport [inference]

negative regulation of nucleobase-containing compound transport [inference]

negative regulation of RNA export from nucleus

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

regulation of nucleocytoplasmic transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

negative regulation of RNA export from nucleus

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

negative regulation of transport [inference]

negative regulation of nucleobase-containing compound transport [inference]

negative regulation of RNA export from nucleus

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

regulation of cellular process [inference]

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

regulation of nucleocytoplasmic transport [inference]

negative regulation of nucleocytoplasmic transport [inference]

negative regulation of RNA export from nucleus

regulation of RNA export from nucleus [inference]

negative regulation of RNA export from nucleus

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
nucleus	IEA
nuclear envelope	ISO
nuclear envelope	IEA
annulate lamellae	ISO
nuclear pore	ISO

GO Hierarchy

cellular component

protein-containing complex

nuclear protein-containing complex [inference]

cellular anatomical structure [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

nuclear inclusion body

membrane

annulate lamellae

organelle membrane [inference]

nuclear membrane

organelle envelope [inference]

nuclear envelope

nuclear periphery

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nucleolus

nucleoplasmic side of nuclear pore

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
DNA binding
chromatin binding	ISO
double-stranded DNA binding	ISO
nuclear localization sequence binding	ISO
nuclear localization sequence binding	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of nuclear pore

binding [inference]

nucleic acid binding [inference]

DNA binding

double-stranded DNA binding

chromatin binding

protein binding [inference]

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

peptide binding [inference]

signal sequence binding [inference]

nuclear localization sequence binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

nuclear pore complex protein

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
RNA export from nucleus
metal ion binding
nuclear localization sequence binding
protein import into nucleus

Displaying **all 4** entries
InterPro
Nuclear pore complex protein
Nucleoporin Nup153, N-terminal
Zinc finger, RanBP2-type superfamily
Zinc finger, RanBP2-type

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	32630	FB:FBgn0061200
Homo sapiens	9972	HGNC:8062

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Last updated: April 6, 2026

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Acknowledgements