GlyCosmos Portal

Submissions

tight junction protein 2

Summary

Gene Symbol

Tjp2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

21873

KEGG Gene ID

PubChem

21873

Alliance of Genome Resources

MGI:1341872

Annotation

Keyword

3D-structure
Cell membrane
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
SH3 domain
Tight junction

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9Z0U1	Tight junction protein ZO-2 Zona occludens protein 2 Zonula occludens protein 2
A0A3B2WCN9	Tight junction protein ZO-2 Zona occludens protein 2 Zonula occludens protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
negative regulation of tumor necrosis factor-mediated signaling pathway	IMP
homotypic cell-cell adhesion	ISO
cell-cell junction organization	IBA
intestinal absorption	ISO
establishment of endothelial intestinal barrier	ISO

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

homotypic cell-cell adhesion

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier [inference]

establishment of endothelial intestinal barrier

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

cell-cell junction organization

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

regulation of vascular permeability [inference]

positive regulation of vascular permeability [inference]

positive regulation of blood-brain barrier permeability

regulation of blood-brain barrier permeability [inference]

positive regulation of blood-brain barrier permeability

digestive system process [inference]

intestinal absorption

developmental process [inference]

anatomical structure development [inference]

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier [inference]

establishment of endothelial intestinal barrier

cellular developmental process [inference]

cell development [inference]

epithelial cell development [inference]

endothelial cell development [inference]

establishment of endothelial barrier [inference]

establishment of endothelial intestinal barrier

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to cell junction [inference]

protein localization to cell-cell junction

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of multicellular organismal process [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of response to cytokine stimulus [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of tumor necrosis factor-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of cytokine-mediated signaling pathway [inference]

negative regulation of tumor necrosis factor-mediated signaling pathway

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

regulation of biological quality [inference]

regulation of vascular permeability [inference]

positive regulation of vascular permeability [inference]

positive regulation of blood-brain barrier permeability

regulation of blood-brain barrier permeability [inference]

positive regulation of blood-brain barrier permeability

regulation of membrane permeability

Displaying entries **6 - 10** of 19 in total

« First

‹ Prev

1

2

3

4

Next ›

Last »
GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA
cell-cell junction	IDA
adherens junction	IEA
gap junction	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cell surface

membrane [inference]

plasma membrane

cell junction

anchoring junction [inference]

cell-cell junction

tight junction

bicellular tight junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
protein binding	IPI
protein domain specific binding	ISO
protein-macromolecule adaptor activity	ISO
transmembrane transporter binding	ISO
cell adhesion molecule binding	IBA