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MIRAGE
FAT atypical cadherin 1
Summary
- Gene Symbol
-
- FAT1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Calcium
- Cell adhesion
- Cell membrane
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Nucleus
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q14517 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| lens development in camera-type eye | ||
| epithelial cell morphogenesis | ||
| establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis | ||
| actin filament organization | ||
| cell adhesion |
GO Hierarchy
biological process
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| cytosol | ||
| plasma membrane | ||
| cell-cell junction | ||
| focal adhesion |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| calcium ion binding | ||
| protein binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- cadherin
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| calcium ion binding |
| homophilic cell adhesion via plasma membrane adhesion molecules |
| InterPro |
|---|
| Cadherin conserved site |
| Cadherin-like superfamily |
| Cadherin-like |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050866 | oral squamous cell carcinoma | |
| DOID:3748 | esophagus squamous cell carcinoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:5409 | lung small cell carcinoma | |
| DOID:9256 | colorectal cancer |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2195 | Xenbase:XB-GENE-920279 | ||
| 2196 | FB:FBgn0261574 | ||
| 14107 | Xenbase:XB-GENE-920279 | MOUSE57640 | |
| 40191 | Xenbase:XB-GENE-920279 | ||
| 65048 | FB:FBgn0261574 | ||
| 83720 | RATNO10789 | ||
| 120114 | FB:FBgn0261574 | ||
| 175590 | Xenbase:XB-GENE-920279 | ||
| 191571 | FB:FBgn0261574 | ||
| 245827 | FB:FBgn0261574 |
