Fc gamma receptor IIIa

Summary
Gene Symbol
  • FCGR3A
Organism
Homo sapiens (human)
NCBI Gene
2214
PubChem
2214
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Cell membrane
  • Disulfide bond
  • Glycoprotein
  • IgG-binding protein
  • Immunity
  • Immunoglobulin domain
  • Phosphoprotein
  • Proteomics identification
  • Receptor
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Transmembrane helix
Proteins
Displaying all 2 entries
UniProt Protein Name
P08637
  • CD16-II
  • CD16a antigen
  • Fc-gamma RIII-alpha
  • FcR-10
  • IgG Fc receptor III-2
H0Y755
Gene Ontology (GO)
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
low affinity immunoglobulin gamma Fc region receptor III
Functional Category
  • G: Carbohydrate transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • O: Posttranslational modification, protein turnover, chaperones
Displaying 1 entry
Gene Ontology
cell surface receptor signaling pathway
Displaying 1 entry
InterPro
Immunoglobulin-like domain
Disease
Disease Ontology
Displaying entries 1 - 10 of 25 in total
DO ID Disease Name Source
DOID:0050908 myelodysplastic syndrome
DOID:0060901 lymphoplasmacytic lymphoma
DOID:0080162 lupus nephritis
DOID:0081267 graft-versus-host disease
DOID:0111941 immunodeficiency 20
DOID:1205 allergic disease
DOID:13241 Behcet's disease
DOID:13375 temporal arteritis
DOID:1389 polyneuropathy
DOID:1587 thrombocytopenia due to platelet alloimmunization
Ortholog
Displaying entries 41 - 43 of 43 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
103746771 NANGA21032
106831116 EQUAS32395
113883690 BOBOX06713

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025