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Fc gamma receptor and transporter

Summary

Gene Symbol

FCGRT

Organism

Homo sapiens (human)

External Links

NCBI Gene

2217

KEGG Gene ID

[""]

PubChem

2217

Alliance of Genome Resources

HGNC:3621

Annotation

Keyword

3D-structure
Cell membrane
Direct protein sequencing
Disulfide bond
Endosome
Glycoprotein
IgG-binding protein
Immunoglobulin domain
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A024QZI2	IgG Fc fragment receptor transporter alpha chain Neonatal Fc receptor
P55899	IgG Fc fragment receptor transporter alpha chain Neonatal Fc receptor
M0R0A9	IgG Fc fragment receptor transporter alpha chain Neonatal Fc receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor	NAS
immune response	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

vesicle-mediated transport [inference]

transcytosis [inference]

immunoglobulin transcytosis in epithelial cells [inference]

IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor

multicellular organismal process [inference]

transcytosis [inference]

immunoglobulin transcytosis in epithelial cells [inference]

IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor

response to stimulus [inference]

immune response

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

transcytosis [inference]

immunoglobulin transcytosis in epithelial cells [inference]

IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
extracellular region	IBA
obsolete extracellular space
plasma membrane	IEA
external side of plasma membrane	IBA
endosome membrane	EXP

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

side of membrane [inference]

external side of plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI
IgG binding	IDA
beta-2-microglobulin binding	IBA
beta-2-microglobulin binding	IEA
peptide antigen binding	ISS

GO Hierarchy

molecular function

binding [inference]

antigen binding [inference]

peptide antigen binding

protein binding

beta-2-microglobulin binding

peptide binding [inference]

peptide antigen binding

protein-containing complex binding [inference]

immunoglobulin binding [inference]

IgG binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

H-2 class I histocompatibility antigen, alpha chain

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
immune response

Displaying **all 8** entries
InterPro
Immunoglobulin C1-set
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Immunoglobulin/major histocompatibility complex, conserved site
MHC class I-like antigen recognition-like superfamily
MHC class I-like antigen recognition-like
MHC classes I/II-like antigen recognition protein