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CDC42 binding protein kinase alpha

Summary

Gene Symbol

Cdc42bpa

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

226751

KEGG Gene ID

PubChem

226751

Alliance of Genome Resources

MGI:2441841

Annotation

Keyword

ATP-binding
Alternative splicing
Cell projection
Coiled coil
Cytoplasm
Phosphoprotein
Proteomics identification
Reference proteome
Serine/threonine-protein kinase
Zinc-finger

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q3UU96	CDC42-binding protein kinase alpha
H7BX44	CDC42-binding protein kinase alpha
E9PVY0	CDC42-binding protein kinase alpha
A0A1D5RLQ9	CDC42-binding protein kinase alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	IMP
protein phosphorylation	ISO
cytoskeleton organization	ISO
cytoskeleton organization	IEA
nuclear migration	IMP

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

actin filament-based process [inference]

actin cytoskeleton organization

actomyosin structure organization

cell motility [inference]

cell migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization

microtubule cytoskeleton organization

actin cytoskeleton organization

actomyosin structure organization

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear migration

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear migration

establishment of organelle localization [inference]

nuclear migration

organelle localization [inference]

nucleus localization [inference]

nuclear migration

establishment of organelle localization [inference]

nuclear migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
cytoplasm	IBA
cytoplasm	IEA
cytoskeleton	IBA
cell-cell junction	ISO

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

cell junction [inference]

anchoring junction [inference]

cell-cell junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

organelle [inference]

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
magnesium ion binding	ISO
protein kinase activity	IEA
protein serine/threonine kinase activity	ISO
protein serine/threonine kinase activity	IBA
protein serine/threonine kinase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

transition metal ion binding [inference]

zinc ion binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

MRCK alpha

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
ATP binding
actomyosin structure organization
cytoskeleton organization
kinase activity
metal ion binding
nucleotide binding
phosphorylation
transferase activity

Displaying entries **1 - 10** of 14 in total

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InterPro
AGC-kinase, C-terminal
C1-like domain superfamily
CRIB domain
Citron homology (CNH) domain
KELK-motif containing domain
Myotonic dystrophy protein kinase, coiled coil
PH-like domain superfamily
Pleckstrin homology domain
Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Protein kinase domain