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adhesion G protein-coupled receptor L1

Summary

Gene Symbol

ADGRL1

Organism

Homo sapiens (human)

External Links

NCBI Gene

22859

KEGG Gene ID

PubChem

22859

Alliance of Genome Resources

HGNC:20973

Annotation

Keyword

Alternative splicing
Autism spectrum disorder
Autocatalytic cleavage
Cell membrane
Cell projection
Disease variant
Disulfide bond
G-protein coupled receptor
Glycoprotein
Intellectual disability
Lectin
Methylation
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Synaptosome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O94910	Calcium-independent alpha-latrotoxin receptor 1 Latrophilin-1 Lectomedin-2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	TAS
G protein-coupled receptor signaling pathway	IBA
G protein-coupled receptor signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	EXP
plasma membrane	IBA
plasma membrane	IEA
membrane	TAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell junction [inference]

synapse

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

axon

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GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	IEA
G protein-coupled receptor activity	TAS
G protein-coupled receptor activity	IBA
G protein-coupled receptor activity	IEA
protein binding	IPI

GO Hierarchy

molecular function

binding [inference]

protein binding

cell adhesion molecule binding

carbohydrate binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

adhesion G protein-coupled receptor L2

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
cell surface receptor signaling pathway

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InterPro
D-galactoside/L-rhamnose binding SUEL lectin domain superfamily
D-galactoside/L-rhamnose binding SUEL lectin domain
GAIN domain superfamily
GAIN domain, N-terminal
GPCR family 2, extracellular hormone receptor domain superfamily
GPCR, family 2, extracellular hormone receptor domain
GPCR, family 2, latrophilin, C-terminal
GPCR, family 2, latrophilin
GPCR, family 2, secretin-like, conserved site
GPCR, family 2, secretin-like