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MIRAGE
purinergic receptor P2X 2
Summary
- Gene Symbol
-
- P2RX2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Cell membrane
- Disease variant
- Disulfide bond
- Glycoprotein
- Hearing
- Ligand-gated ion channel
- Non-syndromic deafness
- Proteomics identification
- Receptor
- Reference proteome
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia |
|
|
| response to ischemia |
|
|
| detection of hypoxic conditions in blood by carotid body chemoreceptor signaling |
|
|
| monoatomic ion transport |
|
|
| ion transport |
|
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
|
| plasma membrane |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| purinergic nucleotide receptor activity |
|
|
| purinergic nucleotide receptor activity |
|
|
| extracellularly ATP-gated monoatomic cation channel activity |
|
|
| extracellularly ATP-gated monoatomic cation channel activity |
|
|
| extracellularly ATP-gated monoatomic cation channel activity |
|
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110567 | autosomal dominant nonsyndromic deafness 41 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources |
|---|---|---|
| 231602 | MGI:2665170 | |
| 114115 | RGD:620251 | |
| 387297 | ZFIN:ZDB-GENE-030319-2 | |
| 108715297 | Xenbase:XB-GENE-17346343 | |
| 101730278 | Xenbase:XB-GENE-6043718 |
