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apoptotic chromatin condensation inducer 1

Summary

Gene Symbol

ACIN1

Organism

Homo sapiens (human)

External Links

NCBI Gene

22985

KEGG Gene ID

PubChem

22985

Alliance of Genome Resources

HGNC:17066

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Apoptosis
Direct protein sequencing
Isopeptide bond
Methylation
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Ubl conjugation
mRNA splicing

Proteins

Displaying **all 4** entries
UniProt	Protein Name
E7EQT4
S4R3H4
B4DQZ7
Q9UKV3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
mRNA processing
apoptotic process
RNA splicing	IBA
erythrocyte differentiation	IEP
apoptotic chromosome condensation	IDA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA processing

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

mRNA metabolic process [inference]

mRNA processing

RNA processing [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

chromosome condensation [inference]

apoptotic chromosome condensation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

myeloid cell differentiation [inference]

erythrocyte differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of multicellular organismal process [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of cellular process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of mRNA metabolic process [inference]

regulation of mRNA processing

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of RNA splicing [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of mRNA splicing, via spliceosome [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of cellular process [inference]

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of RNA splicing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of mRNA metabolic process [inference]

negative regulation of mRNA processing [inference]

negative regulation of mRNA splicing, via spliceosome

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of multicellular organismal development [inference]

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of myeloid cell differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

regulation of monocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

positive regulation of hemopoiesis [inference]

positive regulation of leukocyte differentiation [inference]

positive regulation of myeloid leukocyte differentiation [inference]

positive regulation of monocyte differentiation

Displaying entries **6 - 10** of 15 in total

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GO Term	Evidence Code	PMID
nucleolus	IEA
cytosol	TAS
plasma membrane
nuclear speck	IDA
nuclear speck	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

ASAP complex

nuclear protein-containing complex [inference]

exon-exon junction complex

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

nuclear lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

nucleolus

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

nucleolus

nuclear body [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

supramolecular complex [inference]

ribonucleoprotein granule [inference]

nuclear ribonucleoprotein granule [inference]

nuclear speck

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleic acid binding	NAS
nucleic acid binding	IEA
RNA binding	HDA
protein binding	IPI
ATP hydrolysis activity	NAS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

nucleic acid binding

RNA binding

protein binding

enzyme binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Apoptotic chromatin condensation inducer

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 5** entries
InterPro
Acin1, RNSP1-SAP18 binding (RSB) motif
Acinus, RNA recognition motif
RNA-binding domain superfamily
SAP domain superfamily
SAP domain

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Mus musculus	56215	MGI:1891824

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements