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MIRAGE

CCR4-NOT transcription complex subunit 1

Summary

Gene Symbol

CNOT1

Organism

Homo sapiens (human)

External Links

NCBI Gene

23019

KEGG Gene ID

PubChem

23019

Alliance of Genome Resources

HGNC:7877

Annotation

Keyword

3D-structure
Alternative splicing
Autism spectrum disorder
Cytoplasm
Developmental protein
Disease variant
Holoprosencephaly
Intellectual disability
Nucleus
Phosphoprotein
Proteomics identification
RNA-mediated gene silencing
Reference proteome
Repressor
Transcription regulation
Translation regulation

Proteins

Displaying 1 entry
UniProt	Protein Name
A5YKK6	CCR4-associated factor 1 Negative regulator of transcription subunit 1 homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

1

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Last »
GO Term	Evidence Code	PMID
negative regulation of transcription by RNA polymerase II	IDA
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	IBA
nuclear-transcribed mRNA poly(A) tail shortening	NAS
trophectodermal cell differentiation	IEA
positive regulation of cytoplasmic mRNA processing body assembly	IDA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

mRNA metabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

nucleic acid catabolic process [inference]

RNA catabolic process [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

cellular developmental process [inference]

cell differentiation [inference]

trophectodermal cell differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

trophectodermal cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular estrogen receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of retinoic acid receptor signaling pathway [inference]

negative regulation of retinoic acid receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of translation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular estrogen receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of retinoic acid receptor signaling pathway [inference]

negative regulation of retinoic acid receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

regulation of developmental process [inference]

regulation of stem cell population maintenance

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of intracellular estrogen receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

regulation of retinoic acid receptor signaling pathway [inference]

negative regulation of retinoic acid receptor signaling pathway

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA poly(A) tail shortening [inference]

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of translation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA poly(A) tail shortening [inference]

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

negative regulation of translation

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA poly(A) tail shortening [inference]

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of translation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA poly(A) tail shortening [inference]

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

positive regulation of RNA metabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of mRNA metabolic process [inference]

regulation of mRNA catabolic process [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA poly(A) tail shortening [inference]

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

regulation of protein metabolic process [inference]

regulation of translation [inference]

negative regulation of translation

negative regulation of protein metabolic process [inference]

negative regulation of translation

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

regulation of organelle assembly [inference]

regulation of cytoplasmic mRNA processing body assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of mRNA metabolic process [inference]

positive regulation of mRNA catabolic process

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

positive regulation of cellular component biogenesis [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process [inference]

post-transcriptional gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

negative regulation of translation

regulatory ncRNA-mediated gene silencing [inference]

regulatory ncRNA-mediated post-transcriptional gene silencing [inference]

miRNA-mediated post-transcriptional gene silencing

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of protein metabolic process [inference]

negative regulation of translation

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of RNA metabolic process [inference]

negative regulation of RNA biosynthetic process [inference]

negative regulation of DNA-templated transcription [inference]

negative regulation of transcription by RNA polymerase II

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of intracellular steroid hormone receptor signaling pathway [inference]

negative regulation of intracellular estrogen receptor signaling pathway

negative regulation of retinoic acid receptor signaling pathway

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

regulation of organelle assembly [inference]

regulation of cytoplasmic mRNA processing body assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of organelle assembly [inference]

positive regulation of cytoplasmic mRNA processing body assembly

regulation of multicellular organismal process [inference]

regulation of stem cell population maintenance

regulation of biological quality [inference]

regulation of RNA stability [inference]

regulation of mRNA stability [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [inference]

positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

RNA destabilization [inference]

mRNA destabilization [inference]

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
P-body	ISS
P-body	IDA
P-body	IBA
P-body	IEA
extracellular region	HDA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

cellular anatomical structure [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

membraneless organelle [inference]

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

P-body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular membraneless organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

P-body

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

P-body

Displaying entries **1 - 5** of 9 in total

1

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GO Term	Evidence Code	PMID
RNA binding	HDA
poly(A)-specific ribonuclease activity	IDA
protein binding	IPI
protein domain specific binding	IPI
nuclear estrogen receptor binding	IDA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

exonuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-RNA exonuclease activity [inference]

poly(A)-specific ribonuclease activity

3'-5' exonuclease activity [inference]

3'-5'-RNA exonuclease activity [inference]

poly(A)-specific ribonuclease activity

catalytic activity, acting on a nucleic acid [inference]

nuclease activity [inference]

exonuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-RNA exonuclease activity [inference]

poly(A)-specific ribonuclease activity

3'-5' exonuclease activity [inference]

3'-5'-RNA exonuclease activity [inference]

poly(A)-specific ribonuclease activity

RNA nuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-RNA exonuclease activity [inference]

poly(A)-specific ribonuclease activity

catalytic activity, acting on RNA [inference]

RNA nuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5'-RNA exonuclease activity [inference]

poly(A)-specific ribonuclease activity

binding [inference]

nucleic acid binding [inference]

RNA binding

protein binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

nuclear receptor binding [inference]

protein domain specific binding

armadillo repeat domain binding

molecular adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0081398	holoprosencephaly 12	Alliance of Genome Resources
DOID:0081397	Vissers-Bodmer syndrome	Alliance of Genome Resources

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Mus musculus	234594	MGI:2442402

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Last updated: April 6, 2026