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MIRAGE
cytoplasmic FMR1 interacting protein 1
Summary
- Gene Symbol
-
- CYFIP1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Actin-binding
- Alternative splicing
- Cell projection
- Cell shape
- Cytoplasm
- Developmental protein
- Differentiation
- Direct protein sequencing
- Neurogenesis
- Phosphoprotein
- Reference proteome
- Synaptosome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q7L576 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| Rac protein signal transduction | ||
| negative regulation of translation | ||
| lamellipodium assembly | ||
| lamellipodium assembly | ||
| regulation of actin filament polymerization |
GO Hierarchy
- regulation of myelination
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of cellular component biogenesis [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| ruffle | ||
| extracellular region | ||
| cytosol | ||
| focal adhesion | ||
| lamellipodium |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA 7-methylguanosine cap binding | ||
| protein binding | ||
| translation repressor activity | ||
| small GTPase binding | ||
| small GTPase binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- cytoplasmic FMR1-interacting protein
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| RNA 7-methylguanosine cap binding |
| cell projection assembly |
| regulation of actin filament polymerization |
| InterPro |
|---|
| CYRIA/CYRIB, Rac1 binding domain |
| Cytoplasmic FMR1-interacting |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:5419 | schizophrenia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 107585188 | SINGR21826 | ||
| 108271765 | ICTPU02110 | ||
| 108520530 | RHIBE40385 | ||
| 110212742 | PHACI04525 | ||
| 113440869 | PSETE12665 | ||
| 113476269 | ATHCN02546 | ||
| 113574607 | ELEEL14915 | ||
| 113900671 | BOBOX37585 | ||
| 114041158 | VOMUR27875 | ||
| 114596347 | PODMU19396 |
