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MIRAGE
Rho guanine nucleotide exchange factor 10
Summary
- Gene Symbol
-
- Arhgef10
- Organism
- Mus musculus (house mouse)
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| myelination in peripheral nervous system |
|
|
| myelination in peripheral nervous system |
|
|
| actin cytoskeleton organization |
|
|
| positive regulation of Rho protein signal transduction |
|
|
| positive regulation of Rho protein signal transduction |
|
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasm |
|
|
| cytoplasm |
|
|
| centrosome |
|
|
| centrosome |
|
|
| centrosome |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| guanyl-nucleotide exchange factor activity |
|
|
| guanyl-nucleotide exchange factor activity |
|
|
| guanyl-nucleotide exchange factor activity |
|
|
| kinesin binding |
|
|
| kinesin binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Rho guanine nucleotide exchange factor 10
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| actin cytoskeleton organization |
| positive regulation of stress fiber assembly |
| InterPro |
|---|
| Dbl homology (DH) domain superfamily |
| Dbl homology (DH) domain |
| Rho guanine nucleotide exchange factor 10/17 |
| WD40-repeat-containing domain superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder |
