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protein kinase C and casein kinase substrate in neurons 1

Summary

Gene Symbol

Pacsin1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

23969

KEGG Gene ID

PubChem

23969

Alliance of Genome Resources

MGI:1345181

Annotation

Keyword

3D-structure
Cell membrane
Cell projection
Coiled coil
Cytoplasm
Cytoplasmic vesicle
Direct protein sequencing
Endocytosis
Lipid-binding
Phosphoprotein
Reference proteome
SH3 domain
Synaptosome

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q61644	Syndapin-1
Q543Y7
Q3TYF2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
endocytosis
cytoskeleton organization	ISO
cytoskeleton organization	IBA
actin filament organization	IEA
signal transduction	TAS

GO Hierarchy

biological process

cellular process [inference]

signal transduction

vesicle-mediated transport [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular developmental process [inference]

cell development [inference]

neuron development

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane tubulation

supramolecular fiber organization [inference]

actin filament organization

developmental process [inference]

anatomical structure morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

anatomical structure development [inference]

cell development [inference]

neuron development

cellular developmental process [inference]

cell development [inference]

neuron development

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

protein localization to membrane

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

import into cell [inference]

endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of localization in cell [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane

protein localization to plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

negative regulation of endocytosis

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

regulation of postsynaptic neurotransmitter receptor internalization

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

positive regulation of developmental process [inference]

positive regulation of dendrite development

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

negative regulation of transport [inference]

negative regulation of endocytosis

regulation of developmental process [inference]

regulation of dendrite development [inference]

positive regulation of dendrite development

positive regulation of developmental process [inference]

positive regulation of dendrite development

regulation of cellular process [inference]

signal transduction

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

regulation of cellular component organization [inference]

regulation of endocytosis

negative regulation of endocytosis

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

regulation of postsynaptic neurotransmitter receptor internalization

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

regulation of dendrite development [inference]

positive regulation of dendrite development

negative regulation of cellular component organization [inference]

negative regulation of endocytosis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of dendrite development

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

negative regulation of endocytosis

regulation of receptor-mediated endocytosis [inference]

regulation of receptor internalization [inference]

regulation of postsynaptic neurotransmitter receptor internalization

regulation of biological quality [inference]

regulation of postsynaptic neurotransmitter receptor internalization

Displaying entries **6 - 10** of 25 in total

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GO Term	Evidence Code	PMID
cytosol	IEA
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

synaptic membrane [inference]

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse

ribbon synapse [inference]

photoreceptor ribbon synapse

glutamatergic synapse

leading edge membrane [inference]

ruffle membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

myelin sheath

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Golgi-associated vesicle [inference]

COPI-coated vesicle

coated vesicle [inference]

COPI-coated vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Golgi-associated vesicle [inference]

COPI-coated vesicle

coated vesicle [inference]

COPI-coated vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

Golgi-associated vesicle [inference]

COPI-coated vesicle

coated vesicle [inference]

COPI-coated vesicle

neuron projection terminus [inference]

axon terminus

perinuclear region of cytoplasm

presynapse [inference]

axon terminus

presynaptic endocytic zone

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein binding	IPI
phospholipid binding	ISO
phospholipid binding	IDA
phospholipid binding	IBA
phospholipid binding	IEA

GO Hierarchy

phospholipid binding

Gene Ontology information from NCBI Gene and UniProt.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Acknowledgements