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arachidonate 5-lipoxygenase activating protein

Summary

Gene Symbol

ALOX5AP

Organism

Homo sapiens (human)

External Links

NCBI Gene

241

KEGG Gene ID

PubChem

241

Annotation

Keyword

3D-structure
Endoplasmic reticulum
Leukotriene biosynthesis
Nucleus
Proteomics identification
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A087WW23	MK-886-binding protein
P20292	FLAP MK-886-binding protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
leukotriene production involved in inflammatory response
leukotriene metabolic process	IEA
leukotriene biosynthetic process	IDA
leukotriene biosynthetic process	IBA
leukotriene biosynthetic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

icosanoid metabolic process [inference]

leukotriene metabolic process

leukotriene biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

carboxylic acid biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process

icosanoid biosynthetic process [inference]

leukotriene biosynthetic process

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to calcium ion

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotrimerization

protein trimerization [inference]

protein homotrimerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotrimerization

protein trimerization [inference]

protein homotrimerization

cellular detoxification [inference]

cellular oxidant detoxification

multicellular organismal process [inference]

production of molecular mediator involved in inflammatory response [inference]

arachidonate metabolite production involved in inflammatory response [inference]

leukotriene production involved in inflammatory response

response to stimulus [inference]

response to chemical [inference]

response to metal ion [inference]

response to calcium ion [inference]

cellular response to calcium ion

cellular response to metal ion [inference]

cellular response to calcium ion

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to calcium ion

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to metal ion [inference]

cellular response to calcium ion

detoxification [inference]

cellular detoxification [inference]

cellular oxidant detoxification

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
nuclear envelope	TAS
nuclear envelope	IDA
nuclear envelope	IBA
endoplasmic reticulum	IDA
endoplasmic reticulum	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
glutathione transferase activity	IBA
leukotriene-C4 synthase activity	IBA
glutathione peroxidase activity	IBA
protein binding	IPI
enzyme activator activity	IEA