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Guidelines

MIRAGE

agouti signaling protein

Summary

Gene Symbol

Asip

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24152

KEGG Gene ID

[""]

PubChem

24152

Alliance of Genome Resources

RGD:2003

Annotation

Keyword

Disulfide bond
Glycoprotein
Knottin
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q99JA2	Agouti switch protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
generation of precursor metabolites and energy
biological_process	ND
adult feeding behavior
hormone-mediated signaling pathway	IEA
melanosome transport

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

hormone-mediated signaling pathway

metabolic process [inference]

generation of precursor metabolites and energy

biosynthetic process [inference]

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

phenol-containing compound metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

phenol-containing compound biosynthetic process [inference]

melanin biosynthetic process

secondary metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

secondary metabolite biosynthetic process [inference]

melanin biosynthetic process

pigment metabolic process [inference]

melanin metabolic process [inference]

melanin biosynthetic process

pigment biosynthetic process [inference]

melanin biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

epigenetic regulation of gene expression

epigenetic programming of gene expression [inference]

epigenetic programming in the zygotic pronuclei

organelle organization [inference]

vesicle organization [inference]

pigment granule organization [inference]

melanosome organization

multicellular organismal process [inference]

behavior [inference]

feeding behavior [inference]

adult feeding behavior

adult behavior [inference]

adult feeding behavior

pigmentation

localization [inference]

establishment of localization [inference]

transport [inference]

pigment granule transport [inference]

melanosome transport

establishment of localization in cell [inference]

establishment of vesicle localization [inference]

establishment of pigment granule localization [inference]

establishment of melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

establishment of pigment granule localization [inference]

establishment of melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

organelle localization [inference]

vesicle localization [inference]

establishment of vesicle localization [inference]

establishment of pigment granule localization [inference]

establishment of melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

pigment granule localization [inference]

melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

establishment of pigment granule localization [inference]

establishment of melanosome localization [inference]

melanosome transport

pigment granule transport [inference]

melanosome transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

hormone-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

positive regulation of biosynthetic process [inference]

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression

epigenetic programming of gene expression [inference]

epigenetic programming in the zygotic pronuclei

regulation of secondary metabolite biosynthetic process [inference]

regulation of melanin biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of secondary metabolic process [inference]

regulation of secondary metabolite biosynthetic process [inference]

regulation of melanin biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

epigenetic regulation of gene expression

epigenetic programming of gene expression [inference]

epigenetic programming in the zygotic pronuclei

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of secondary metabolite biosynthetic process [inference]

positive regulation of melanin biosynthetic process

negative regulation of cellular process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of secondary metabolite biosynthetic process [inference]

negative regulation of melanin biosynthetic process

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of G protein-coupled receptor signaling pathway [inference]

negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway

Displaying **all 5** entries
GO Term	Evidence Code	PMID
extracellular region	ISS
extracellular region	ISO
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

Displaying entries **1 - 5** of 7 in total

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2

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GO Term	Evidence Code	PMID
signaling receptor binding	IEA
neuropeptide hormone activity	IBA
melanocortin receptor binding	IBA
type 3 melanocortin receptor binding
type 4 melanocortin receptor binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

G protein-coupled receptor binding [inference]

neuropeptide receptor binding [inference]

melanocortin receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity [inference]

neuropeptide hormone activity

neuropeptide activity [inference]

neuropeptide hormone activity

signaling receptor inhibitor activity [inference]

receptor antagonist activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity [inference]

neuropeptide hormone activity

neuropeptide activity [inference]

neuropeptide hormone activity

molecular function inhibitor activity [inference]

signaling receptor inhibitor activity [inference]

receptor antagonist activity

Gene Ontology information from NCBI Gene and UniProt.

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Last updated: April 6, 2026