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adrenoceptor alpha 2C

Summary

Gene Symbol

Adra2c

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24175

KEGG Gene ID

PubChem

24175

Alliance of Genome Resources

RGD:2058

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P22086	Alpha-2 adrenergic receptor subtype C4 Alpha-2C adrenoreceptor
A6IK05	Alpha-2 adrenergic receptor subtype C4 Alpha-2C adrenoreceptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
regulation of smooth muscle contraction	IEA
epidermal growth factor receptor signaling pathway	ISO
G protein-coupled receptor signaling pathway	ISO
G protein-coupled receptor signaling pathway	IEA
female pregnancy	IMP

GO Hierarchy

biological process

cellular process [inference]

cell activation [inference]

platelet activation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

G protein-coupled receptor signaling pathway

adrenergic receptor signaling pathway

reproductive process [inference]

multi-organism reproductive process [inference]

female pregnancy

multicellular organismal process [inference]

cell activation [inference]

platelet activation

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction

positive regulation of vasoconstriction

multi-multicellular organism process [inference]

female pregnancy

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

regulation of secretion by cell [inference]

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of secretion by cell [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of amine transport [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

regulation of amine transport [inference]

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of amine transport [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of secretion by cell [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of transport [inference]

negative regulation of secretion [inference]

negative regulation of secretion by cell [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of amine transport [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of multicellular organismal process [inference]

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction [inference]

negative regulation of uterine smooth muscle contraction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

cell surface receptor protein tyrosine kinase signaling pathway [inference]

ERBB signaling pathway [inference]

epidermal growth factor receptor signaling pathway

G protein-coupled receptor signaling pathway

adrenergic receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

regulation of neuron differentiation [inference]

positive regulation of neuron differentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of cell differentiation [inference]

positive regulation of neuron differentiation

negative regulation of cellular process [inference]

negative regulation of secretion by cell [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

regulation of secretion by cell [inference]

regulation of catecholamine secretion [inference]

regulation of norepinephrine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

negative regulation of secretion by cell [inference]

negative regulation of catecholamine secretion [inference]

negative regulation of norepinephrine secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of smooth muscle contraction

negative regulation of smooth muscle contraction [inference]

negative regulation of uterine smooth muscle contraction

regulation of uterine smooth muscle contraction

negative regulation of uterine smooth muscle contraction

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction [inference]

negative regulation of uterine smooth muscle contraction

regulation of blood circulation [inference]

regulation of vasoconstriction

positive regulation of vasoconstriction

positive regulation of multicellular organismal process [inference]

positive regulation of vasoconstriction

negative regulation of multicellular organismal process [inference]

negative regulation of muscle contraction [inference]

negative regulation of smooth muscle contraction [inference]

negative regulation of uterine smooth muscle contraction

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction

positive regulation of vasoconstriction

Displaying entries **6 - 10** of 13 in total

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GO Term	Evidence Code	PMID
axon	IDA
neuronal cell body	IDA
axon terminus	IDA
postsynaptic membrane	IDA
postsynaptic density membrane	EXP

GO Hierarchy

cellular component

cellular anatomical structure [inference]

cytoplasm

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

postsynaptic membrane

postsynaptic specialization membrane [inference]

postsynaptic density membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

cell body [inference]

neuronal cell body

neuron projection terminus [inference]

axon terminus

presynapse [inference]

axon terminus

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor activity	ISO
G protein-coupled receptor activity	IEA
adrenergic receptor activity	IEA
alpha2-adrenergic receptor activity	ISS
alpha2-adrenergic receptor activity	ISO