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Guidelines
MIRAGE
CF transmembrane conductance regulator

Summary
Gene Symbol
  • Cftr
Organism
Rattus norvegicus (Norway rat)
NCBI Gene
24255
PubChem
24255
Alliance of Genome Resources
Annotation
Keyword
  • ATP-binding
  • Cell membrane
  • Chloride channel
  • Endoplasmic reticulum
  • Endosome
  • Glycoprotein
  • Isomerase
  • Nucleus
  • Palmitate
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Transmembrane helix
  • Ubl conjugation
Proteins
Displaying all 3 entries
UniProt Protein Name
A6IE40
  • ATP-binding cassette sub-family C member 7
  • Channel conductance-controlling ATPase
  • cAMP-dependent chloride channel
P34158
  • ATP-binding cassette sub-family C member 7
  • Channel conductance-controlling ATPase
  • cAMP-dependent chloride channel
A0A0G2K3B1
  • ATP-binding cassette sub-family C member 7
  • Channel conductance-controlling ATPase
  • cAMP-dependent chloride channel
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 68 in total
GO Term Evidence Code PMID
cholesterol biosynthetic process
monoatomic ion transport
ion transport
chloride transport
chloride transport
GO Hierarchy
Displaying entries 1 - 5 of 40 in total
GO Term Evidence Code PMID
nucleus
nucleus
cytoplasm
cytoplasm
early endosome
GO Hierarchy
Displaying entries 1 - 5 of 33 in total
GO Term Evidence Code PMID
chloride channel activity
chloride channel activity
chloride channel activity
intracellularly ATP-gated chloride channel activity
intracellularly ATP-gated chloride channel activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
multidrug resistance-associated
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • K: Transcription
  • T: Signal transduction mechanisms
Displaying all 3 entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding
Displaying all 6 entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase
Alliance of Genome Resources
Expression
Displaying all 6 entries
Location References
Disease
Disease Ontology
Displaying all 5 entries
DO ID Disease Name Source
DOID:0111862 congenital bilateral absence of vas deferens
DOID:10808 gastric ulcer
DOID:1485 cystic fibrosis
DOID:1724 duodenal ulcer
DOID:693 dental enamel hypoplasia
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026