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surfactant protein A1

Summary

Gene Symbol

Sftpa1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

24773

PubChem

24773

Alliance of Genome Resources

RGD:3665

Annotation

Keyword

3D-structure
Calcium
Collagen
Direct protein sequencing
Disulfide bond
Extracellular matrix
Glycoprotein
Hydroxylation
Lectin
Metal-binding
Reference proteome
Repeat
Signal
Surface film

Proteins

Displaying 1 entry
UniProt	Protein Name
P08427

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
response to hypoxia	IEP	14756961
respiratory gaseous exchange by respiratory system	IEA
circadian rhythm	IEP	12872443
opsonization	ISO
response to hormone	IEP	9779374

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

opsonization

cellular process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to nitric oxide

cellular response to nitrogen compound [inference]

cellular response to reactive nitrogen species [inference]

cellular response to nitric oxide

cellular response to oxygen-containing compound [inference]

cellular response to nitric oxide

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

multicellular organismal process [inference]

respiratory gaseous exchange by respiratory system

rhythmic process [inference]

circadian rhythm

response to stimulus [inference]

response to stress [inference]

response to external stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin A

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

cellular response to external stimulus [inference]

cellular response to mechanical stimulus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to abiotic stimulus [inference]

response to mechanical stimulus [inference]

cellular response to mechanical stimulus

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to increased oxygen levels [inference]

response to hyperoxia

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

response to endogenous stimulus [inference]

response to hormone

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to growth factor [inference]

response to epidermal growth factor

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin A

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to cytokine [inference]

response to interleukin-6

response to inorganic substance [inference]

cellular response to inorganic substance [inference]

cellular response to nitric oxide

response to nitric oxide [inference]

cellular response to nitric oxide

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to nitric oxide

cellular response to nitrogen compound [inference]

cellular response to reactive nitrogen species [inference]

cellular response to nitric oxide

cellular response to oxygen-containing compound [inference]

cellular response to nitric oxide

response to nitrogen compound [inference]

response to nitric oxide [inference]

cellular response to nitric oxide

cellular response to nitrogen compound [inference]

cellular response to reactive nitrogen species [inference]

cellular response to nitric oxide

response to oxygen-containing compound [inference]

response to nitric oxide [inference]

cellular response to nitric oxide

cellular response to oxygen-containing compound [inference]

cellular response to nitric oxide

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to inorganic substance [inference]

cellular response to nitric oxide

cellular response to nitrogen compound [inference]

cellular response to reactive nitrogen species [inference]

cellular response to nitric oxide

cellular response to oxygen-containing compound [inference]

cellular response to nitric oxide

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to mechanical stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis

regulation of phagocytosis [inference]

positive regulation of phagocytosis

Displaying **all 5** entries
GO Term	Evidence Code	PMID
collagen trimer	IEA
extracellular space	IDA	11472975
extracellular space	IBA
multivesicular body	IDA	16187065
multivesicular body	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

collagen trimer

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome [inference]

multivesicular body

Displaying **all 2** entries
GO Term	Evidence Code	PMID
carbohydrate binding	IEA
metal ion binding	IEA

GO Hierarchy

molecular function

binding [inference]

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

C-type LECtin

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
C-type lectin fold
C-type lectin-like/link domain superfamily
C-type lectin-like

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
multivesicular body	PMID:16187065
extracellular space	PMID:11472975

Ortholog

Displaying entries **21 - 30** of 49 in total

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Species	Gene ID	Orthologous MAtrix
Pan troglodytes	740759	PANTR01004
Equus caballus	100033826	HORSE15033
Ornithorhynchus anatinus	100075818	ORNAN17715
Cavia porcellus	100135615	CAVPO18491
Callithrix jacchus	100397920	CALJA06206
Pongo abelii	100442206	PONAB01916
Pongo abelii	100446496	PONAB01914
Cricetulus griseus	100757798	CRIGR14359
Sarcophilus harrisii	100923918	SARHA11884
Pan paniscus	100986067	PANPA05028