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MIRAGE

ADP-ribosylarginine hydrolase

Summary

Gene Symbol

Adprh

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

25371

KEGG Gene ID

PubChem

25371

Alliance of Genome Resources

RGD:2052

Annotation

Keyword

Direct protein sequencing
Hydrolase
Magnesium
Metal-binding
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q02589	ADP-ribose-L-arginine cleaving enzyme [Protein ADP-ribosylarginine] hydrolase
A6IR67	ADP-ribose-L-arginine cleaving enzyme [Protein ADP-ribosylarginine] hydrolase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein modification process	IMP
protein de-ADP-ribosylation	ISS
protein de-ADP-ribosylation	ISO
protein de-ADP-ribosylation	IBA
protein de-ADP-ribosylation	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein de-ADP-ribosylation

macromolecule modification [inference]

protein modification process

protein de-ADP-ribosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process

protein de-ADP-ribosylation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IDA
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

Displaying entries **1 - 5** of 12 in total

1

2

3

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Last »
GO Term	Evidence Code	PMID
magnesium ion binding	ISS
magnesium ion binding	ISO
magnesium ion binding	IEA
ADP-ribosylarginine hydrolase activity	ISS
ADP-ribosylarginine hydrolase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

ADP-ribosylarginine hydrolase activity

catalytic activity, acting on a protein [inference]

ADP-ribosylarginine hydrolase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

alkali metal ion binding [inference]

potassium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ADP-ribosylarginine hydrolase

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
P: Inorganic ion transport and metabolism

Displaying **all 3** entries
Gene Ontology
ADP-ribosylarginine hydrolase activity
hydrolase activity
magnesium ion binding

Displaying **all 3** entries
InterPro
ADP-ribosylarginine hydrolase
ADP-ribosylation/Crystallin J1 superfamily
ADP-ribosylation/Crystallin J1

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
extracellular space	PMID:9037477

Rhea

H₂O

ADP-D-ribose

Enzyme

3.2.2.19

PMID

H₂O + N^ω-(ADP-D-ribosyl)-L-arginine

L-arginine + ADP-D-ribose

Enzyme

3.2.2.19

PMID

Ortholog

Displaying **all 2** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	11544	MGI:1098234
Homo sapiens	141	HGNC:269

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026