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autophagy-associated lipase Atg15

Summary

Gene Symbol

atg15

Organism

Schizosaccharomyces pombe (fission yeast)

External Links

NCBI Gene

2541924

KEGG Gene ID

PubChem

2541924

Annotation

Keyword

Autophagy
Endosome
Glycoprotein
Hydrolase
Lipid degradation
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O13934	Autophagy-related protein 15

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
lipid metabolic process	IEA
phosphatidylserine catabolic process	IBA
macroautophagy	IMP
multivesicular body membrane disassembly	IBA
piecemeal microautophagy of the nucleus	IBA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

catabolic process [inference]

autophagy [inference]

macroautophagy

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

primary metabolic process [inference]

lipid metabolic process

neutral lipid metabolic process [inference]

neutral lipid catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

membrane disassembly [inference]

multivesicular body membrane disassembly

membrane organization [inference]

membrane disassembly [inference]

multivesicular body membrane disassembly

Displaying **all 4** entries
GO Term	Evidence Code	PMID
fungal-type vacuole lumen	ISO
vacuolar lumen	IBA
membrane	IBA
multivesicular body membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane [inference]

multivesicular body membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

late endosome membrane [inference]

multivesicular body membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen

fungal-type vacuole lumen

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glycerophospholipase activity	IBA
phosphatidylcholine lysophospholipase A1 activity	ISO
triacylglycerol lipase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

triacylglycerol lipase activity

phospholipase activity [inference]

glycerophospholipase activity

A1-type glycerophospholipase activity [inference]

lysophospholipase A1 activity [inference]

phosphatidylcholine lysophospholipase A1 activity

carboxylic ester hydrolase activity [inference]

triacylglycerol lipase activity

A1-type glycerophospholipase activity [inference]

lysophospholipase A1 activity [inference]

phosphatidylcholine lysophospholipase A1 activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:12044

H₂O + a triacylglycerol

H⁺ + a diacylglycerol + a fatty acid

Enzyme

PMID

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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